The three-orphan nuclear receptor 4A genes are induced by diverse stressors and stimuli,
and there is increasing evidence that NR4A1 (Nur77), NR4A2 (Nurr1), and NR4A3 (Nor1) …

Abstract Glycogen synthase kinase‐3 (GSK3), consisting of GSK3α and GSK3β subtypes, is
a complex protein kinase that regulates numerous substrates. Research has observed …

Cocaine use disorder (CUD) is an intractable syndrome, and rising overdose death rates
represent a substantial public health crisis that exacts tremendous personal and financial …

Background: Psilocybin is a serotonergic psychedelic found in “magic mushrooms” with a
putative therapeutic potential for treatment-resistant depression, anxiety, obsessive …

Background Global changes in gene expression underlying circuit and behavioral
dysregulation associated with cocaine addiction remain incompletely understood. Here, we …

Endogenous homeostatic mechanisms can restore normal neuronal function following
cocaine-induced neuroadaptations. Such mechanisms may be exploited to develop novel …

Here, we used RNA capture-seq to identify a large population of lncRNAs that are
expressed in the infralimbic prefrontal cortex of adult male mice in response to fear-related …

Memory consolidation involves discrete patterns of transcriptional events in the
hippocampus. Despite the emergence of single-cell transcriptomic profiling techniques …

Histone deacetylase (HDAC) inhibitors may have therapeutic utility in multiple neurological
and psychiatric disorders, but the underlying mechanisms remain unclear. Here, we identify …

Aging is accompanied by cognitive deficits, including impairments in long-term memory
formation. Understanding the molecular mechanisms that support preserved cognitive …