Hypoxia is a hallmark of malignant tumors and often correlates with increasing tumor
aggressiveness and poor treatment outcomes. Therefore, early diagnosis and effective …

Once thought to be a remnant of cell division, the midbody (MB) has recently been shown to
have roles beyond its primary function of orchestrating abscission. Despite the emerging …

Drug carrier systems based on mesoporous inorganic nanoparticles generally face the
problem of fast clearance from bloodstream thus failing in passive and active targeting to …

Although treatment of colorectal cancer with 5-florouracil and oxaliplatin is widely used, it is
frequently followed by a relapse. Therefore, there is an urgent need for profound …

Background/Aim: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of
cancer, particularly due to its aggressive course and challenging diagnostics in early-stage …

Survival rates from pancreatic cancer have remained stagnant for decades due to the
heterogenic nature of the disease. This study aimed to find a new advanced biomarker and …

The recombinant phage tail sheath protein, gp053, from Escherichia coli infecting myovirus
vB_EcoM_FV3 (FV3) was able to self-assemble into long, ordered and extremely stable …

Introduction: Hepatocellular carcinoma (HCC) is recognized as the fifth most common
neoplasm and currently represents the second leading form of cancer-related death …

Abstract Treatment of acute myeloid leukemia (AML) is still a challenge because of common
relapses or resistance to treatment. Therefore, the development of new therapeutic …

Calreticulin (CALR) is a highly conserved multifunctional chaperone protein primarily
present in the endoplasmic reticulum, where it regulates Ca 2+ homeostasis. Recently …