Burkitt lymphoma (BL) is an aggressive form of B cell lymphoma that can affect children and
adults. The study of BL led to the identification of the first recurrent chromosomal aberration …

Hematological malignancies are a highly heterogeneous group of diseases with varied
molecular and phenotypical characteristics. SWI/SNF (SWItch/Sucrose Non-Fermentable) …

With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Diffuse large B cell lymphoma (DLBCL) is the most common B cell non-Hodgkin lymphoma
and remains incurable in around 40% of patients. Efforts to sequence the coding genome …

Primary lymphomas of the central nervous system (PCNSL) are mainly diffuse large B-cell
lymphomas (DLBCLs) confined to the central nervous system (CNS). Molecular drivers of …

Burkitt lymphoma (BL) accounts for most pediatric non-Hodgkin lymphomas, being less
common but significantly more lethal when diagnosed in adults. Much of the knowledge of …

Richter syndrome (RS) is the transformation of chronic lymphocytic leukemia (CLL) into
aggressive lymphoma, most commonly diffuse large B-cell lymphoma (DLBCL). We …

Abstract MYC translocation occurs in 8–14% of diffuse large B-cell lymphoma (DLBCL), and
may concur with BCL2 and/or BCL6 translocation, known as double-hit (DH) or triple-hit …

Diffuse large B-cell lymphoma is the most common lymphoma worldwide. Both
morphologically and prognostically it represents a diverse spectrum of disease. Traditional …

Follicular lymphoma (FL) accounts for∼ 20% of all new lymphoma cases. Increases in
cytological grade are a feature of the clinical progression of this malignancy, and eventual …