Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions

PJ Brennan, M Brigl, MB Brenner - Nature Reviews Immunology, 2013 - nature.com
Invariant natural killer T (iNKT) cells exist in a'poised effector'state, which enables them to
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo

M Tsuji, MS Nair, K Masuda, C Castagna… - Nature …, 2023 - nature.com
Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but
emergence of viral variants that are antigenically distinct from the vaccine strains are of …

Advancing cell-based cancer immunotherapy through stem cell engineering

YR Li, ZS Dunn, Y Yu, M Li, P Wang, L Yang - Cell Stem Cell, 2023 - cell.com
Advances in cell-based therapy, particularly CAR-T cell therapy, have transformed the
treatment of hematological malignancies. Although an important step forward for the field …

The role of natural killer T cells in cancer—a phenotypical and functional approach

D Krijgsman, M Hokland, PJK Kuppen - Frontiers in immunology, 2018 - frontiersin.org
Natural killer T (NKT) cells are a subset of CD1d-restricted T cells at the interface between
the innate and adaptive immune system. NKT cells can be subdivided into functional …

SeXX matters in immunity

JG Markle, EN Fish - Trends in immunology, 2014 - cell.com
The significant contributions of sex to an immune response, specifically in the context of the
sex bias observed in susceptibility to infectious and autoimmune diseases and their …

Raising the NKT cell family

DI Godfrey, S Stankovic, AG Baxter - Nature immunology, 2010 - nature.com
Natural killer T cells (NKT cells) are CD1d-restricted, lipid antigen–reactive,
immunoregulatory T lymphocytes that can promote cell-mediated immunity to tumors and …

Presumed guilty: natural killer T cell defects and human disease

SP Berzins, MJ Smyth, AG Baxter - Nature Reviews Immunology, 2011 - nature.com
Natural killer T (NKT) cells are important regulatory lymphocytes that have been shown in
mouse studies, to have a crucial role in promoting immunity to tumours, bacteria and viruses …

Molecular aspects and future perspectives of cytokine-based anti-cancer immunotherapy

DS Chulpanova, KV Kitaeva, AR Green… - Frontiers in cell and …, 2020 - frontiersin.org
Cytokine-based immunotherapy is a promising field in the cancer treatment, since cytokines,
as proteins of the immune system, are able to modulate the host immune response toward …