The diagnosis and management of cutaneous metastases from melanoma
C Di Raimondo, F Lozzi, PP Di Domenico… - International Journal of …, 2023 - mdpi.com
Melanoma is one of the deadliest skin tumors, accounting for almost 90% of skin cancer
mortality. Although immune therapy and targeted therapy have dramatically changed the …
mortality. Although immune therapy and targeted therapy have dramatically changed the …
Isolated hyperthermic perfusions for cutaneous melanoma in-transit metastasis of the limb and uveal melanoma metastasis to the liver
A Huibers, DK DePalo, MC Perez, JS Zager… - Clinical & Experimental …, 2024 - Springer
Patients with cutaneous melanoma can develop in-transit metastases (ITM), most often
localized to limbs. For patients with uveal melanoma that develop metastatic disease, the …
localized to limbs. For patients with uveal melanoma that develop metastatic disease, the …
Effects of the introduction of modern immunotherapy on the outcome of isolated limb perfusion for melanoma in-transit metastases
CJ Holmberg, J Mattsson, R Olofsson Bagge - Cancers, 2023 - mdpi.com
Simple Summary Melanoma in-transit metastasis has long been effectively treated with
isolated limb perfusion (ILP), a procedure where the limb is treated with high concentrations …
isolated limb perfusion (ILP), a procedure where the limb is treated with high concentrations …
Altered frequencies and functions of innate lymphoid cells in melanoma patients are modulated by immune checkpoints inhibitors
CM Cristiani, M Capone, C Garofalo… - Frontiers in …, 2022 - frontiersin.org
Monoclonal antibodies targeting immune checkpoints improved clinical outcome of patients
with malignant melanoma. However, the mechanisms are not fully elucidated. Since immune …
with malignant melanoma. However, the mechanisms are not fully elucidated. Since immune …
Isolated limb perfusion for locally advanced melanoma in the immunotherapy era
EJ Davies, SJM Reijers, ACJ Van Akkooi… - European Journal of …, 2022 - Elsevier
Background Prior to the advent of effective systemic therapy for melanoma, isolated limb
perfusion (ILP) was the most effective local treatment for advanced in-transit melanoma …
perfusion (ILP) was the most effective local treatment for advanced in-transit melanoma …
Presence of tumor-infiltrating CD8+ T cells and macrophages correlates to longer overall survival in patients undergoing isolated hepatic perfusion for uveal …
J Johansson, J Siarov, R Kiffin, J Mölne… - …, 2020 - Taylor & Francis
Uveal melanoma is a malignant tumor of the eye that often metastasizes to the liver
conferring poor prognosis. When comparing immune profiles in peripheral blood of …
conferring poor prognosis. When comparing immune profiles in peripheral blood of …
C–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model
YH Liu, L Zhu, ZW Zhang, TT Liu, QY Cheng… - Journal of Translational …, 2023 - Springer
Background Previous studies have demonstrated that natural killer (NK) cells migrated into
the liver from peripheral organs and exerted cytotoxic effects on hepatocytes in virus …
the liver from peripheral organs and exerted cytotoxic effects on hepatocytes in virus …