The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents

E Dere, JP Huston, MADS Silva - Neuroscience & Biobehavioral Reviews, 2007 - Elsevier
Rats and mice are attracted by novel objects. They readily approach novel objects and
explore them with their vibrissae, nose and forepaws. It is assumed that such a single …

A unified framework for the functional organization of the medial temporal lobes and the phenomenology of episodic memory

C Ranganath - Hippocampus, 2010 - Wiley Online Library
There is currently an intense debate about the nature of recognition memory and about the
roles of medial temporal lobe subregions in recognition memory processes. At a larger level …

The role of recollection and familiarity in the functional differentiation of the medial temporal lobes

D Montaldi, AR Mayes - Hippocampus, 2010 - Wiley Online Library
The components of the medial temporal lobes (MTL) receive different kinds of input. The
perirhinal cortex receives primarily object/item information, the parahippocampal cortex …

Perirhinal cortex resolves feature ambiguity in complex visual discriminations

TJ Bussey, LM Saksida… - European Journal of …, 2002 - Wiley Online Library
The present experiment tested predictions of a 'perceptual–mnemonic/feature
conjunction'(PMFC) model of perirhinal cortex function. The model predicts that lesions of …

Role of perirhinal cortex in object perception, memory, and associations

EA Murray, BJ Richmond - Current opinion in neurobiology, 2001 - Elsevier
The perirhinal cortex plays a key role in acquiring knowledge about objects. It contributes to
at least four cognitive functions, and recent findings provide new insights into how the …

Transient inactivation of perirhinal cortex disrupts encoding, retrieval, and consolidation of object recognition memory

BD Winters, TJ Bussey - Journal of Neuroscience, 2005 - Soc Neuroscience
Damage to perirhinal cortex (PRh) impairs object recognition memory in humans, monkeys,
and rats when tested in tasks such as delayed nonmatching to sample, visual paired …

Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease

TW Mitchell, EJ Mufson, JA Schneider… - Annals of Neurology …, 2002 - Wiley Online Library
Abnormally phosphorylated tau accumulates as neurofibrillary tangles and neuropil threads
in older persons with and without Alzheimer's disease. The relationship between …

Memory, perception, and the ventral visual‐perirhinal‐hippocampal stream: Thinking outside of the boxes

TJ Bussey, LM Saksida - Hippocampus, 2007 - Wiley Online Library
The prevailing paradigm in cognitive neuroscience assumes that the brain can be best
understood as consisting of modules specialised for different psychological functions. Within …

The organization of visual object representations: a connectionist model of effects of lesions in perirhinal cortex

TJ Bussey, LM Saksida - European Journal of Neuroscience, 2002 - Wiley Online Library
We have developed a simple connectionist model based on the idea that perirhinal cortex
has properties similar to other regions in the ventral visual stream, or 'what'pathway. The …

Cholinergic neurotransmission is essential for perirhinal cortical plasticity and recognition memory

EC Warburton, T Koder, K Cho, PV Massey, G Duguid… - Neuron, 2003 - cell.com
We establish the importance of cholinergic neurotransmission to both recognition memory
and plasticity within the perirhinal cortex of the temporal lobe. The muscarinic receptor …