Occlusion of coronary artery and subsequent damage or death of myocardium can lead to
myocardial infarction (MI) and even heart failure—one of the leading causes of deaths world …

Gene therapy is an innovative approach in the field of regenerative medicine. This therapy
entails the transfer of genetic material into a patient's cells to treat diseases. In particular …

The reprogramming of induced cardiomyocytes (iCMs) has shown potential in regenerative
medicine. However, in vivo reprogramming of iCMs is significantly inefficient, and novel …

To date, no viable therapeutic options exist for the effective and sustained reversal of cardiac
failure, other than heart transplantation and mechanical circulatory assist devices. Therefore …

The discovery of induced pluripotent stem cells (iPSCs), reprogrammed to pluripotency from
somatic cells, has transformed the landscape of regenerative medicine, disease modelling …

Nonviral direct neuronal reprogramming holds significant potential in the fields of tissue
engineering and regenerative medicine. However, the issue of low reprogramming …

摘要背景: 诱导多能干细胞在疾病模型和再生医学领域具有广阔的应用前景,
能够利用安全高效的方法进行体细胞重编程是诱导多能干细胞广泛应用于临床的前提 …

The search for cell-based strategies to repair the injured heart after ischemic injury has led
to the discovery of methods for genetic and pharmacologic reprogramming of fibroblasts into …

Biorąc pod uwagę filogenetyczny rozwój kręgowców (ssaków, ptaków, ryb), wiele taksonów
reprezentujących typ strunowce (Chordata) oraz podtyp kręgowce (Vertebrata) posiada …

BACKGROUND: Induced pluripotent stem cells (iPSCs) hold enormous potential as a tool to
generate cells for disease modeling and regenerative medicine. The premise for clinical …