Synthesis, crystal structure, Hirshfeld surface analysis, DNA binding, optical and nonlinear optical properties of Schiff bases derived from o-aminophenol

KS Munawar, S Ali, S Muhammad, M Ashfaq… - Journal of Molecular …, 2023 - Elsevier
The current work focuses on the synthesis of the two new Schiff base ligands derived from o-
aminophenol named 2-[(E)-(3-chlorophenyl) methylidene] amino-phenol (2AP3Cl) and 4 …

Shedding light on the synthesis, crystal structure, characterization, and computational study of optoelectronic properties and bioactivity of imine derivatives

M Ashfaq, MN Tahir, S Muhammad, KS Munawar… - ACS …, 2022 - ACS Publications
Two imine compounds named as (E)-2-(((3, 4-dichlorophenyl) imino) methyl) phenol
(DC2H) and (E)-4-(((2, 4-dimethylphenyl) imino) methyl) phenol (DM4H) are synthesized …

Synthesis, Solvent effects, Chemical reactivity, Molecular Docking and Molecular Dynamic Studies of Triazole derivative

G Venkatesh, Y Sixto-López, P Vennila, V Siva… - Journal of Molecular …, 2024 - Elsevier
In the present study,(E)-3-(2-(4-amino-5-mercapto-4H-1, 2, 4-triazol-3-yl) hydrazono) methyl)-
2-bromo-6-methoxyphenol (AMTMP) is synthesized and characterized utilizing FT-IR, FT …

Evaluation of indole-picolinamide hybrid molecules as carbonic anhydrase-II inhibitors: Biological and computational studies

S Zaib, I Khan, HS Anbar, SO Zaraei… - Journal of Molecular …, 2022 - Elsevier
The present study reports the successful synthesis and evaluation of a series of indole-
picolinamide hybrids as potent inhibitors of bovine carbonic anhydrase II, a promising …

Metalloenzymes: Potential Drug Targets

J Iqbal, C Jacob, J Sévigny - Frontiers in Pharmacology, 2021 - frontiersin.org
Metalloenzymes have an important role in the regulation of many biological functions.
Overexpressed and/or reduced secretion of such enzymes lead to different complications of …

Serendipitous N, S-difunctionalization of triazoles with trifluoromethyl-β-diketones: access to regioisomeric 1-trifluoroacetyl-3-aryl-5-(2-oxo-2-arylethylthio)-1, 2, 4 …

R Aggarwal, P Kumar, M Hooda, S Kumar - RSC advances, 2024 - pubs.rsc.org
In the present research work, a serendipitous regioselective synthesis of DNA targeting
agents, 1-trifluoroacetyl-3-aryl-5-(2-oxo-2-arylethylthio)-1, 2, 4-triazoles, has been achieved …