Unraveling the interplay between vital organelle stress and oxidative stress in idiopathic pulmonary fibrosis

A Mohanan, KR Washimkar, MN Mugale - Biochimica et Biophysica Acta …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized
by excessive accumulation of extracellular matrix, leading to irreversible fibrosis. Emerging …

Longitudinal assessment of bleomycin-induced pulmonary fibrosis by evaluating TGF-β1/Smad2, Nrf2 signaling and metabolomic analysis in mice

KR Washimkar, MS Tomar, C Kulkarni, S Verma… - Life Sciences, 2023 - Elsevier
Introduction Pulmonary fibrosis (PF) is characterized by an increase in collagen synthesis
and deposition of extracellular matrix. Several factors, including transforming growth factor …

Regeneration capability of neonatal lung-derived decellularized extracellular matrix in an emphysema model

K Devi, MS Tomar, M Barsain, A Shrivastava… - Journal of Controlled …, 2024 - Elsevier
Impaired and limited alveolar regeneration upon injury advances pulmonary disorders and
irreversibly affects millions of people worldwide. Adult mammals do not have a strong …

[HTML][HTML] Effects and mechanisms of N6-methyladenosine RNA methylation in environmental pollutant-induced carcinogenesis

T Li, Z Xu, K Zhang, X Yang, A Thakur, S Zeng… - Ecotoxicology and …, 2024 - Elsevier
Environmental pollution, including air pollution, plastic contamination, and heavy metal
exposure, is a pressing global issue. This crisis contributes significantly to pollution-related …

Azadirachtin Attenuates Carcinogen Benzo (a) Pyrene-Induced DNA Damage, Cell Cycle Arrest, Apoptosis, Inflammatory, Metabolic, and Oxidative Stress in HepG2 …

A John, H Raza - Antioxidants, 2023 - mdpi.com
Azadirachtin (AZD), a limonoid from the versatile, tropical neem tree (Azadirachta indica), is
well known for its many medicinal, and pharmacological effects. Its effects as an anti-oxidant …

Effects and Mechanisms of Fucoxanthin from Hizikia fusiforme on Inhibiting Tongue Squamous Cell Carcinoma Proliferation via AKT/mTOR‐Mediated Glycolysis

XQ Zhang, TY Liu, LT Zhang, ZH Hua… - Journal of Food …, 2023 - Wiley Online Library
Fucoxanthin, a natural carotenoid, contains special ene bonds and 5, 6‐mono‐epoxide
compounds in its molecule, which has physiological activities such as anticancer …

Osteogenic effect of an adiponectin-derived short peptide that rebalances bone remodeling: a potential disease-modifying approach for postmenopausal osteoporosis …

S Rajput, C Kulkarni, S Sharma, MS Tomar… - Archives of Pharmacal …, 2024 - Springer
Adiponectin, an adipokine, regulates metabolic processes, including glucose flux, lipid
breakdown, and insulin response, by activating adiponectin receptors 1 and 2 (AdipoR1 and …

A unique circ_0067716/EIF4A3 double-negative feedback loop impacts malignant transformation of human bronchial epithelial cells induced by benzo (a) pyrene

S Zhao, M Xiao, L Li, H Zhang, M Shan, S Cui… - Science of The Total …, 2024 - Elsevier
Benzo (a) pyrene as a pervasive environmental contaminant is characterized by its
substantial genotoxicity, and epidemiological investigations have established a correlation …

[HTML][HTML] Unraveling In vivo Potential of Curcumin-loaded Graphene Quantum Dots on Drug Delivery and Release Kinetics Aspects of Cancer Treatment

MZ Fahmi, SFA Sugito, A Wibrianto… - …, 2024 - pmc.ncbi.nlm.nih.gov
This study introduces an innovative magnetic-based multifunctional anti-cancer drug carrier
aiming to enhance the efficacy of curcumin in cancer therapy. The research investigates the …

Beta-alanine promotes angiogenesis in laser-induced choroidal neovascularization mice models

JL Wu, M Zhang, XD Sun - International Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
AIM To investigate the effect of β-alanine (BA) on laser-induced choroidal
neovascularization (CNV) mice models. METHODS Laser-induced CNV mice models were …