Relevance of KCNJ5 in Pathologies of Heart Disease
KM Meyer, N Malhotra, J Kwak… - International journal of …, 2023 - mdpi.com
Abnormalities in G-protein-gated inwardly rectifying potassium (GIRK) channels have been
implicated in diseased states of the cardiovascular system; however, the role of GIRK4 (Kir3 …
implicated in diseased states of the cardiovascular system; however, the role of GIRK4 (Kir3 …
Long qt syndrome and sinus bradycardia–a mini review
R Wilders, AO Verkerk - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Congenital long-QT syndrome (LQTS) is an inherited cardiac disorder characterized by the
prolongation of ventricular repolarization, susceptibility to Torsades de Pointes (TdP), and a …
prolongation of ventricular repolarization, susceptibility to Torsades de Pointes (TdP), and a …
Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation
N Yamada, Y Asano, M Fujita, S Yamazaki, A Inanobe… - Circulation, 2019 - Am Heart Assoc
Background: Bradyarrhythmia is a common clinical manifestation. Although the majority of
cases are acquired, genetic analysis of families with bradyarrhythmia has identified a …
cases are acquired, genetic analysis of families with bradyarrhythmia has identified a …
[HTML][HTML] Mutations of voltage-gated ionic channels and risk of severe cardiac arrhythmias
A Dehghani-Samani… - Acta Cardiologica …, 2019 - ncbi.nlm.nih.gov
Background Arrhythmias as important malfunctions of heart are known as abnormal rhythm
of heart. Several causes can make arrhythmias and most of them are related to generation …
of heart. Several causes can make arrhythmias and most of them are related to generation …
Mitochondrial calcium uniporter deficiency in zebrafish causes cardiomyopathy with arrhythmia
AD Langenbacher, H Shimizu, W Hsu, Y Zhao… - Frontiers in …, 2020 - frontiersin.org
Mitochondrial Ca2+ uptake influences energy production, cell survival, and Ca2+ signaling.
The mitochondrial calcium uniporter, MCU, is the primary route for uptake of Ca2+ into the …
The mitochondrial calcium uniporter, MCU, is the primary route for uptake of Ca2+ into the …
The relevance of GIRK channels in heart function
A Campos-Ríos, L Rueda-Ruzafa, JA Lamas - Membranes, 2022 - mdpi.com
Among the large number of potassium-channel families implicated in the control of neuronal
excitability, G-protein-gated inwardly rectifying potassium channels (GIRK/Kir3) have been …
excitability, G-protein-gated inwardly rectifying potassium channels (GIRK/Kir3) have been …
Gene expression networks in the murine pulmonary myocardium provide insight into the pathobiology of atrial fibrillation
JK Boutilier, RL Taylor, T Mann… - G3: Genes …, 2017 - academic.oup.com
The pulmonary myocardium is a muscular coat surrounding the pulmonary and caval veins.
Although its definitive physiological function is unknown, it may have a pathological role as …
Although its definitive physiological function is unknown, it may have a pathological role as …
Sinus Node Disease and Cardiac Conduction Disease
PA Schweizer - Channelopathies in Heart Disease, 2018 - Springer
Primary sinus node disease (SND) and cardiac conduction defect (CCD) are frequent
clinical entities with significant morbidity and mortality, which are major indications for the …
clinical entities with significant morbidity and mortality, which are major indications for the …
Born to be bradycardic?
J Lian, GX Yan, PR Kowey - Cardiology, 2010 - search.ebscohost.com
Born to Be Bradycardic? Page 1 Fax +41 61 306 12 34 E-Mail karger@karger.ch www.karger.com
Editorial Comment Cardiology 2010;115:229–231 DOI: 10.1159/000297573 Born to Be …
Editorial Comment Cardiology 2010;115:229–231 DOI: 10.1159/000297573 Born to Be …