Highlights•Targeting specific organelles treat or decrease symptoms of several diseases.•
Manipulation of nanomaterials characteristics can improve the intracellular …

Objectives The main objective of present review is to explore and evaluate the effectiveness
of recently developed methods to improve the bioavailability of orally administered …

Budesonide (BUD) is used as first choice therapy for the treatment of allergic rhinitis, a
chronic allergic-immune condition with an increased incidence in the pediatric population …

Thiolated cyclodextrins (CDs) are obtained by covalent attachment of thiol moieties on the
oligomeric backbone of different types of CDs. First, thiolated CDs were introduced in the …

This study aims to design an anionic, thiolated cellulose derivative and to evaluate its
mucoadhesive and permeation-enhancing properties utilizing enoxaparin as a model drug …

This study aimed to develop the Fenugreek seed mucilage-based pH-responsive hydrogel
system in order to improve the oral bioavailability of methotrexate (MTX). Fenugreek seed …

Abstract Chitosan-1-(mercaptomethyl)-cyclopropane acetic acid (CS-MCA) copolymer was
synthesized by amino linkage. The obtained copolymer was characterized by FTIR, 1 H …

The present study aims at in vitro antibacterial and antioxidant activity evaluation of chitosan
modified with monomethyl fumaric acid (MFA) using 1-ethyl-3-(3-dimethylaminopropyl) …

The purpose of the study was to develop a per-6-thiolated α-cyclodextrin (α-CD) by
substituting all primary hydroxyl groups of α-CD with thiol groups and to assess its solubility …

Mucoadhesive polymers have an essential role in drug localization and target-specific
actions in oral delivery systems. The current work aims to develop and characterize a new …