[HTML][HTML] Copper homeostasis and copper-induced cell death: novel targeting for intervention in the pathogenesis of vascular aging

Z Chen, Y Li, X Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Copper-induced cell death, also known as cuproptosis, is distinct from other types of cell
death such as apoptosis, necrosis, and ferroptosis. It can trigger the accumulation of lethal …

[HTML][HTML] Cyclin-dependent kinase inhibitors in the rare subtypes of melanoma therapy

J Kaszubski, M Gagat, A Grzanka, A Wawrzyniak… - Molecules, 2024 - mdpi.com
Melanoma occurs in various forms and body areas, not only in the cutis, but also in mucous
membranes and the uvea. Rarer subtypes of that cancer differ in genomic aberrations, which …

Cell Senescence and the Genetics of Melanoma Development

SM Constantinou, DC Bennett - Genes, Chromosomes and …, 2024 - Wiley Online Library
Cutaneous malignant melanoma is an aggressive skin cancer with an approximate lifetime
risk of 1 in 38 in the UK. While exposure to ultraviolet radiation is a key environmental risk …

Comparative Analysis of the Effect of the BRAF Inhibitor Dabrafenib in 2D and 3D Cell Culture Models of Human Metastatic Melanoma Cells

D Tovar-Parra, M Zammit-Mangion - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Melanoma, a variant of skin cancer, presents the highest mortality rates
among all skin cancers. Despite advancements in targeted therapies, immunotherapies, and …

Genetic Characteristics of Primary Cutaneous Malignant Melanoma in Koreans Compared With Western Populations

H Jang, HJ Ryu, SK Kim - in vivo, 2023 - iv.iiarjournals.org
Abstract Background/Aim: Cutaneous melanoma, a melanocyte malignancy, can be divided
into many clinical subtypes that differ in presentation, demographics, and genetic profile. In …

[PDF][PDF] Solute Carrier Family 45 Member 2 Germline Variants in the Colombian Population with Melanoma

DG Garay, LD Gutierrez-Castañeda… - Journal of Skin and …, 2022 - brieflands.com
Background: The solute carrier family 45-member 2 (SLC45A2) gene, located on
chromosome 5p13. 2, is involved in melanin biosynthesis. Single-nucleotide variants (SNVs) …

SLC45A2 Germilne Variants in Colombian Population with Melanoma

D Garcia-Garay, D Parra-Tovar… - 2022 - researchsquare.com
The SLC45A2 gene, located at chromosome 5p13. 2, is involved in melanin biosynthesis.
Single Nucleotide Variant (SNVs) in this gene have been associated with normal variation of …