Identification of new psychoactive substances and their metabolites using non-target detection with high-resolution mass spectrometry through diagnosing fragment …

JM Matey, F Zapata, LM Menéndez-Quintanal… - Talanta, 2023 - Elsevier
During the last decade, forensic toxicologists have evidenced an exponential increase in the
number of new psychoactive substances (NPS) that are available on the drug market …

Chemical classification of new psychoactive substances (NPS)

F Zapata, JM Matey, G Montalvo, C García-Ruiz - Microchemical Journal, 2021 - Elsevier
This work comprehensively reviews some fundamental concepts about drugs, especially
focusing on new psychoactive substances (NPS), and their typical classifications based on …

Toxicology and analysis of psychoactive tryptamines

S Malaca, AF Lo Faro, A Tamborra, S Pichini… - International Journal of …, 2020 - mdpi.com
Our understanding of tryptamines is poor due to the lack of data globally. Tryptamines
currently are not part of typical toxicology testing regimens and their contribution to drug …

Recent advances of liquid chromatography–(tandem) mass spectrometry in clinical and forensic toxicology—an update

D Remane, DK Wissenbach, FT Peters - Clinical biochemistry, 2016 - Elsevier
Liquid chromatography (LC) coupled to mass spectrometry (MS) or tandem mass
spectrometry (MS/MS) is a well-established and widely used technique in clinical and …

Development and validation of a rapid LC‐MS/MS method for the detection of 182 novel psychoactive substances in whole blood

A Giorgetti, R Barone, G Pelletti… - Drug testing and …, 2022 - Wiley Online Library
Introduction The analysis of novel psychoactive substances (NPS) represents a challenge in
forensic toxicology, due to the high number of compounds characterized by different …

Annual banned‐substance review: analytical approaches in human sports drug testing

M Thevis, T Kuuranne, H Geyer… - Drug testing and …, 2017 - Wiley Online Library
There has been an immense amount of visibility of doping issues on the international stage
over the past 12 months with the complexity of doping controls reiterated on various …

Clinical value of analytical testing in patients presenting with new psychoactive substances intoxication

KE Grafinger, ME Liechti… - British journal of clinical …, 2020 - Wiley Online Library
New psychoactive substances (NPS) have emerged worldwide in recent years, posing a
threat to public health and a challenge to drug policy. NPS are usually derivatives or …

[HTML][HTML] Microextraction by packed sorbent of synthetic tryptamines from urine and ion mobility spectrometry determination

M Aparici-Lozano, S Armenta, S Garrigues… - Advances in Sample …, 2023 - Elsevier
A procedure for the determination of N, N-dipropyltryptamine, 5‑methoxy-N, N-
dimethyltryptamine, and 5‑methoxy-N-methyl-N-isopropyltryptamine in urine has been …

[HTML][HTML] Analysis of drugs including illicit and new psychoactive substances in oral fluids by gas chromatography-drift tube ion mobility spectrometry

A Denia, FA Esteve-Turrillas, S Armenta - Talanta, 2022 - Elsevier
In this study, a gas chromatograph (GC) has been coupled to a drift tube ion mobility
spectrometer (IMS) in order to develop an analytical procedure for the determination of …

Determination of 74 new psychoactive substances in serum using automated in-line solid-phase extraction-liquid chromatography-tandem mass spectrometry

S Lehmann, T Kieliba, J Beike, M Thevis… - … of Chromatography B, 2017 - Elsevier
A detailed description is given of the development and validation of a fully automated in-line
solid-phase extraction-liquid chromatography-tandem mass spectrometry (SPE-LC–MS/MS) …