Histone demethylases in the regulation of immunity and inflammation

L Qu, T Yin, Y Zhao, W Lv, Z Liu, C Chen, K Liu… - Cell Death …, 2023 - nature.com
Pathogens or danger signals trigger the immune response. Moderate immune response
activation removes pathogens and avoids excessive inflammation and tissue damage …

Gut immune microenvironment and autoimmunity

Q Wang, Q Lu, S Jia, M Zhao - International Immunopharmacology, 2023 - Elsevier
A variety of immune cells or tissues are present in the gut to form the gut immune
microenvironment by interacting with gut microbiota, and to maintain the gut immune …

N6-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m6A/PD-L1 manner

Y Wang, P Jin, X Wang - Apoptosis, 2024 - Springer
Increasing data and literature have illustrated that tumor immune escape represents a major
source of tumor formation and recrudesce. Besides, novel findings also indicate that RNA …

The role of histone methylase and demethylase in antitumor immunity: a new direction for immunotherapy

Y Zhang, J Chen, H Liu, R Mi, R Huang, X Li… - Frontiers in …, 2023 - frontiersin.org
Epigenetic modifications may alter the proliferation and differentiation of normal cells,
leading to malignant transformation. They can also affect normal stimulation, activation, and …

Canine oral squamous cell carcinoma as a spontaneous, translational model for radiation and immunology research

MK Boss, LG Harrison, A Gold, SD Karam… - Frontiers in …, 2023 - frontiersin.org
Introduction Improving outcomes for oral squamous cell carcinoma (OSCC) patients has
been hindered by a lack of effective predictive animal models. Spontaneously occurring …

[HTML][HTML] Loss of YB-1 alleviates liver fibrosis by suppressing epithelial-mesenchymal transition in hepatic progenitor cells

Y Guo, X Xu, H Dong, B Shen, J Zhu, Z Shen… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Previously, we reported that the nuclear translocation of Y-box binding protein 1 (YB-1) is
induced by transforming growth factor-β (TGF-β) and promotes hepatic progenitor cells …