Trends in pretreatment HIV-1 drug resistance in antiretroviral therapy-naive adults in South Africa, 2000–2016: a pooled sequence analysis
B Chimukangara, RJ Lessells, SY Rhee… - …, 2019 - thelancet.com
Abstract Background South Africa has the largest public antiretroviral therapy (ART)
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …
Genotypic and phylogenetic insights on prevention of the spread of HIV-1 and drug resistance in “real-world” settings
BG Brenner, RI Ibanescu, I Hardy, M Roger - Viruses, 2017 - mdpi.com
HIV continues to spread among vulnerable heterosexual (HET), Men-having-Sex with Men
(MSM) and intravenous drug user (IDU) populations, influenced by a complex array of …
(MSM) and intravenous drug user (IDU) populations, influenced by a complex array of …
OLA-Simple: A software-guided HIV-1 drug resistance test for low-resource laboratories
Background HIV drug resistance (HIVDR) testing can assist clinicians in selecting
treatments. However, high complexity and cost of genotyping assays limit routine testing in …
treatments. However, high complexity and cost of genotyping assays limit routine testing in …
[PDF][PDF] Minority HIV-1 drug-resistant mutations and prevention of mother-to-child transmission: perspectives for resource-limited countries
The detection and clinical significance of HIV-1 minority drug-resistant variants is a major
topic of current HIV research. Whereas much attention has been placed on the clinical …
topic of current HIV research. Whereas much attention has been placed on the clinical …
HIV drug resistance levels in adults failing first‐line antiretroviral therapy in an urban and a rural setting in S outh A frica
Objectives Urban and rural HIV treatment programmes face different challenges in the long‐
term management of patients. There are few studies comparing drug resistance profiles in …
term management of patients. There are few studies comparing drug resistance profiles in …
Understanding specific contexts of antiretroviral therapy adherence in rural South Africa: A thematic analysis of digital stories from a community with high HIV …
A Treffry-Goatley, R Lessells, P Sykes… - PLoS …, 2016 - journals.plos.org
Near-perfect adherence to antiretroviral therapy (ART) is required to achieve the best
possible prevention and treatment outcomes. Yet, there have been particular concerns …
possible prevention and treatment outcomes. Yet, there have been particular concerns …
Diagnostic accuracy of pan-degenerate amplification and adaptation assay for HIV-1 drug resistance mutation analysis in low-and middle-income countries
ABSTRACT HIV drug resistance (HIVDR) is a barrier to sustained virologic suppression in
low-and middle-income countries (LMICs). Point mutation assays targeting priority drug …
low-and middle-income countries (LMICs). Point mutation assays targeting priority drug …
HIV-1 drug resistance among Ugandan adults attending an urban out-patient clinic
A von Braun, C Sekaggya-Wiltshire… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Little is known about prevalence of drug resistance among HIV-infected
Ugandans, a setting with over 15 years of public sector access to antiretroviral therapy (ART) …
Ugandans, a setting with over 15 years of public sector access to antiretroviral therapy (ART) …
Community engagement with HIV drug adherence in rural South Africa: a transdisciplinary approach
A Treffry-Goatley, RJ Lessells, R Moletsane… - Medical …, 2018 - mh.bmj.com
Digital storytelling (DST) is an emerging participatory visual method which combines
storytelling traditions with computer and video production technology. In this project, at the …
storytelling traditions with computer and video production technology. In this project, at the …
Implementation of a point mutation assay for HIV drug resistance testing in Kenya
HA Duarte, IA Beck, M Levine, C Kiptinness, JM Kingoo… - Aids, 2018 - journals.lww.com
Objectives: An increasing prevalence of HIV pretreatment drug resistance (PDR) has been
observed in Africa, which could decrease the effectiveness of antiretroviral therapy (ART) …
observed in Africa, which could decrease the effectiveness of antiretroviral therapy (ART) …