Molecular mechanisms of nickel allergy

M Saito, R Arakaki, A Yamada, T Tsunematsu… - International journal of …, 2016 - mdpi.com
Allergic contact hypersensitivity to metals is a delayed-type allergy. Although various metals
are known to produce an allergic reaction, nickel is the most frequent cause of metal allergy …

Human dendritic cell line models for DC differentiation and clinical DC vaccination studies

SJAM Santegoets… - Journal of Leucocyte …, 2008 - academic.oup.com
Dendritic cells (DC) are increasingly applied in the immunotherapy of cancer. As the
development of a standardized DC vaccine product is often hampered by the limited …

[HTML][HTML] Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1

S Jutz, J Leitner, K Schmetterer, I Doel-Perez… - Journal of …, 2016 - Elsevier
Engagement of the T cell receptor complex reprograms T cells for proliferation, cytokine
production and differentiation towards effector cells. This process depends on activating …

Distinct human Langerhans cell subsets orchestrate reciprocal functions and require different developmental regulation

X Liu, R Zhu, Y Luo, S Wang, Y Zhao, Z Qiu, Y Zhang… - Immunity, 2021 - cell.com
Langerhans cells (LCs) play a pivotal role in skin homeostasis, and the heterogeneity of LCs
has long been considered. In this study, we have identified two steady-state (LC1 and LC2) …

miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation

J Jurkin, YM Schichl, R Koeffel, T Bauer… - The Journal of …, 2010 - journals.aai.org
Langerhans cells (LCs) in epithelia and interstitial dendritic cells (intDCs) in adjacent
connective tissues represent two closely related myeloid-derived DC subsets that exert …

Sodium acetate alleviated high-carbohydrate induced intestinal inflammation by suppressing MAPK and NF-κB signaling pathways in Nile tilapia (Oreochromis …

M Li, FC Hu, F Qiao, ZY Du, ML Zhang - Fish & shellfish immunology, 2020 - Elsevier
With the development of aquaculture industry, high-carbohydrate diet is used to stimulate
protein-sparing effect and reduce feed cost. However, fish utilize carbohydrates poorly in …

Liver disease alters high-density lipoprotein composition, metabolism and function

M Trieb, A Horvath, R Birner-Gruenberger… - … et Biophysica Acta (BBA …, 2016 - Elsevier
High-density lipoproteins (HDL) are important endogenous inhibitors of inflammatory
responses. Functional impairment of HDL might contribute to the excess mortality …

[HTML][HTML] A comprehensive and quantitative analysis of the major specificities in rabbit antithymocyte globulin preparations

I Popow, J Leitner, K Grabmeier-Pfistershammer… - American Journal of …, 2013 - Elsevier
Antithymocyte globulin (ATG) preparations are used for treatment and prevention of graft
rejection episodes, graft versus host disease and aplastic anemia. The immunomodulatory …

Dialysis modalities and HDL composition and function

M Holzer, G Schilcher, S Curcic, M Trieb… - Journal of the …, 2015 - journals.lww.com
Lipid abnormalities may have an effect on clinical outcomes of patients on dialysis. Recent
studies have indicated that HDL dysfunction is a hallmark of ESRD. In this study, we …

Aryl hydrocarbon receptor activation inhibits in vitro differentiation of human monocytes and Langerhans dendritic cells

B Platzer, S Richter, D Kneidinger… - The Journal of …, 2009 - journals.aai.org
The transcription factor aryl hydrocarbon receptor (AhR) represents a promising therapeutic
target in allergy and autoimmunity. AhR signaling induced by the newly described ligand …