Idiopathic pulmonary fibrosis (IPF) is a progressive, and ultimately fatal, chronic interstitial
lung disease characterized by enhanced extracellular matrix deposition. Repetitive alveolar …

Idiopathic pulmonary fibrosis (IPF) is a fatal age-associated disease that is characterized by
progressive and irreversible scarring of the lung. The pathogenesis of IPF is not completely …

Background: The presence of emphysema is relatively common in patients with fibrotic
interstitial lung disease. This has been designated combined pulmonary fibrosis and …

Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing
lymphocytes lacking antigen-specific receptors, which include ILC1s and natural killer (NK) …

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and devastating interstitial
lung disease of unknown etiology, where the normal lung architecture is lost and replaced …

Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with
aging that is characterized by the histopathological pattern of usual interstitial pneumonia …

A proportion of patients with certain types of interstitial lung disease (ILD), including chronic
hypersensitivity pneumonitis and ILDs associated with autoimmune diseases, develop a …

Transforming growth factor-β (TGF-β) is extensively involved in the development of fibrosis
in different organs. Overproduction or potentiation of its profibrotic effects leads to an …

A growing body of evidence indicates that aberrant activation of alveolar epithelial cells and
fibroblasts in an aging lung plays a critical role in the pathogenesis of idiopathic pulmonary …

Idiopathic pulmonary fibrosis is a devastating, age-related lung disease of unknown cause
that has few treatment options. This disease was once thought to be a chronic inflammatory …