Background: Antimicrobial resistance is a serious public-health problem throughout the
world. Escherichia coli, the most common Gram-negative microorganism, has developed …

Objectives WGS-based antimicrobial susceptibility testing (AST) is as reliable as phenotypic
AST for several antimicrobial/bacterial species combinations. However, routine use of WGS …

Polymyxins, especially polymyxin B and polymyxin E (colistin), are considered to be the last
line of defence against infections caused by multi-drug-resistant (MDR) gram-negative …

Escherichia coli and other Enterobacteriaceae are diverse species with “open”
pangenomes, where genes move intra-and interspecies via horizontal gene transfer …

Colistin has become the last-line antimicrobial for the treatment of multidrug resistant (MDR)
Enterobacterales in human medicine. To date, several colistin resistance genes have been …

Background Surveillance of commensal Escherichia coli, a possible reservoir of
antimicrobial resistance (AMR) genes, is important as they pose a risk to human and animal …

Combatting antimicrobial resistant (AMR) using a One-Health approach is essential as
various bacteria, including Escherichia coli, a common bacteria, are becoming increasingly …

To tackle the problem of antimicrobial resistance (AMR) surveillance programmes are in
place within Europe applying phenotypic methods, but there are plans for implementing …

Objectives Colistin resistance has emerged worldwide, threatening the efficacy of colistin
treatment of Gram-negative bacterial infections. Farms have been recognised as an …

Background There is ongoing debate regarding potential associations between restrictions
of antimicrobial use and prevalence of antimicrobial resistance (AMR) in bacteria. Objectives …