Since the 2015 WHO classification was introduced into clinical practice,
immunohistochemistry (IHC) has figured prominently in lung cancer diagnosis. In addition to …

Choroidal melanoma (CM), despite its rarity, is the most frequent intraocular malignancy.
Over time, several histological variants of CM have been distinguished, including spindle A …

Advanced and metastatic tumors with complex treatment histories drive cancer mortality.
Here we describe the POG570 cohort, a comprehensive whole-genome, transcriptome and …

The role of cancer stem cells (CSCs) in cancer incidence, drug resistance, and relapse after
chemotherapy has been discussed and it has been confirmed that CSCs are extremely …

Triple-negative breast cancer (TNBC) patients have an increased risk of developing visceral
metastases and other primary nonbreast cancers, particularly lung cancer. The differential …

Simple Summary Triple-negative breast cancer (TNBC) represents a heterogeneous group
of breast cancers that lack estrogen receptor (ER), progesterone receptor (PR), and human …

Purpose For invasive breast cancer (IBC), high SOX10 expression was reported particularly
in TNBC. This raised the possibility that SOX10 may complement other breast markers for …

The SOX genes encode a family of more than 20 transcription factors that are critical
regulators of embryogenesis and developmental processes and, when aberrantly …

Aims Confirmation of a breast origin for triple‐negative breast cancer (TNBC) is sometimes
problematic. The traditional breast markers GATA‐binding protein 3 (GATA3), mammaglobin …

Introduction At present, GATA binding protein 3 (GATA-3) is the most frequently used
diagnostic immunohistochemical (IHC) marker for breast carcinoma (BC). However, it is not …