Abstract Changes in gene copy number are among the most frequent mutational events in
all genomes and were among the mutations for which a physical basis was first known. Yet …

Recent data suggest that, in response to the presence of antibiotics, gene duplication and
amplification (GDA) constitutes an important adaptive mechanism in bacteria. For example …

Dehalococcoides ethenogenes is the only bacterium known to reductively dechlorinate the
groundwater pollutants, tetrachloroethene (PCE) and trichloroethene, to ethene. Its …

Gene duplication-amplification (GDA) processes are highly relevant biologically because
they generate extensive and reversible genetic variation on which adaptive evolution can …

We have investigated to what extent natural transformation acting on free DNA substrates
can facilitate transfer of mobile elements including transposons, integrons and/or gene …

Diversity in adaptive responses is common within species and populations, especially when
the heterogeneity of the frequently large populations found in environments is considered …

When selection is strong and beneficial alleles have a single origin, local reductions in
genetic diversity are expected. However, when beneficial alleles have multiple origins or …

Deformylase inhibitors belong to a novel antibiotic class that targets peptide deformylase, a
bacterial enzyme that removes the formyl group from N-terminal methionine in nascent …

Trichophyton indotineae is an emerging dermatophyte that causes severe tinea corporis and
tinea cruris. Numerous cases of terbinafine-and azole-recalcitrant T. indotineae-related …

We report a genome-wide search of Y-linked genes in Drosophila pseudoobscura. All six
identifiable orthologs of the D. melanogaster Y-linked genes have autosomal inheritance in …