Francisella tularensis is a highly infectious aerosolizable intracellular pathogen that is
capable of causing a debilitating or fatal disease with doses as low as 25 colony-forming …

Tularemia is a zoonosis of humans caused by infection with the facultative intracellular
bacterium Francisella tularensis. Interest in F. tularensis has increased markedly in the past …

The bacterium Vibrio cholerae, like other human pathogens that reside in environmental
reservoirs, survives predation by unicellular eukaryotes. Strains of the O1 and O139 …

Francisella tularensis is a highly infectious, facultative intracellular bacterium which causes
epidemics of tularemia in both humans and mammals at regular intervals. The natural …

Francisella tularensis is a gram-negative, facultative intracellular pathogen that causes the
highly infectious zoonotic disease tularemia. We have discovered a ca. 30-kb pathogenicity …

The facultative intracellular bacterium Francisella tularensis is a highly virulent and
contagious organism, and little is known about its intracellular survival mechanisms. We …

Tularemia is the zoonotic disease caused by the gram-negative coccobacillus Francisella
tularensis. Its wide distribution in the environment poses a challenge for understanding the …

Type VI secretion systems (T6SSs) are newly identified contractile nanomachines that
translocate effector proteins across bacterial membranes. The Francisella pathogenicity …

Francisella tularensis causes the human disease tularemia. F. tularensis is able to survive
and replicate within macrophages, a trait that has been correlated with its high virulence, but …

The Francisella pathogenicity island (FPI) is a cluster of 16–19 genes, which is found
duplicated in most of the Francisella genomes that have been sequenced. Although 16 FPI …