Red blood cells (RBCs), which constitute the most abundant cell type in the body, come in
two distinct flavors-primitive and definitive. Definitive RBCs in mammals circulate as smaller …

This article reviews the regulation of production of RBCs at several levels. We focus on the
regulated expansion of burst-forming unit-erythroid erythroid progenitors by glucocorticoids …

The formation of red blood cells begins with the differentiation of multipotent haematopoietic
progenitors. Reconstructing the steps of this differentiation represents a general challenge in …

Mammals evolved in the face of fluctuating food availability. How the immune system adapts
to transient nutritional stress remains poorly understood. Here, we show that memory T cells …

Gene expression during development and differentiation is regulated in a cell-and stage-
specific manner by complex networks of intergenic and intragenic cis-regulatory elements …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Terminal erythroid differentiation starts from morphologically recognizable proerythroblasts
that proliferate and differentiate to generate red cells. Although this process has been …

SARS-CoV-2 infection is associated with lower blood oxygen levels, even in patients without
hypoxia requiring hospitalization. This discordance illustrates the need for a more unifying …

Osteoblasts are an important component of the hematopoietic microenvironment in bone.
However, the mechanisms by which osteoblasts control hematopoiesis remain unknown …

Red blood cells (RBC s) are generated from haematopoietic stem and progenitor cells
(HSPC s) through the step‐wise process of differentiation known as erythropoiesis. In this …