The goal of obesity management is to improve health. Sustained weight loss of more than
10% overall bodyweight improves many of the complications associated with obesity (eg …

Inflammation contributes to many chronic conditions. It is often associated with circulating
pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity …

Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are increasingly being used to treat
diabetes and obesity. However, their effectiveness and risks have not yet been …

The complex mechanism of colorectal cancer development is closely associated with
epigenetic modifications and is caused by overexpression and/or inactivation of oncogenes …

Background: Status epilepticus (SE) is a series of seizures that can lead to serious
neurological damages. Cannabidiol (CBD) is extracted from the cannabis plant, which has …

Status epilepticus (SE) is a critical medical emergency marked by persistent or rapidly
repeating seizures, posing a threat to life. Using the lithium-pilocarpine-induced SE model …

Ivermectin (IVM) is an antiparasitic drug that primarily works by the activation of GABAA
receptors. The potential pharmacological pathways behind the anti-convulsant effect of IVM …

Introduction Ivermectin (IVM) is an antiparasitic medicine that exerts its function through
glutamate-gated chloride channels and GABA A receptors predominantly. There is paucity of …

Background Idiopathic pulmonary fibrosis (IPF) is a pulmonary fibrotic disease characterized
by a poor prognosis, which its pathogenesis involves the accumulation of abnormal fibrous …

Objectives Epileptiform activity and seizures are present in patients with Alzheimer's disease
(AD) and genetic animal models of AD. Amyloid beta 1-42 (Aβ1-42) oligomers are thought to …