Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation
KC Nicolaou, SA Snyder - Angewandte Chemie International …, 2005 - Wiley Online Library
Over the course of the past half century, the structural elucidation of unknown natural
products has undergone a tremendous revolution. Before World War II, a chemist would …
products has undergone a tremendous revolution. Before World War II, a chemist would …
Marine natural products
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …
literature published in 2002 for marine natural products, with 579 citations (413 for the …
The modified Julia olefination: alkene synthesis via the condensation of metallated heteroarylalkylsulfones with carbonyl compounds
PR Blakemore - Journal of the Chemical Society, Perkin Transactions …, 2002 - pubs.rsc.org
reductive elimination of the β-acyloxysulfone 4 with a single electron donor to afford alkene
products. All four steps can be carried out in a single reaction vessel, although in practice …
products. All four steps can be carried out in a single reaction vessel, although in practice …
Total synthesis of oxacyclic macrodiolide natural products
EJ Kang, E Lee - Chemical reviews, 2005 - ACS Publications
Nature presents us countless numbers of natural products with complex and fascinating
structures and useful properties. Macrodiolides belong to one relatively small but interesting …
structures and useful properties. Macrodiolides belong to one relatively small but interesting …
“K‐synthesis”: recent advancements in natural product synthesis enabled by unique methods and strategies development in Korea
S Han - Bulletin of the Korean Chemical Society, 2023 - Wiley Online Library
Natural product synthesis has lain at the heart of organic chemistry. Complex structures of
natural products have inspired chemists to develop new methods and strategies. The utility …
natural products have inspired chemists to develop new methods and strategies. The utility …
Advances in radical conjugate additions
GSC Srikanth, SL Castle - Tetrahedron, 2005 - Elsevier
Although radicals are usually viewed as neutral, relatively nonpolar species, polar effects in
radical chemistry are wellknown 1 and continue to be exploited in organic synthesis. 2 For …
radical chemistry are wellknown 1 and continue to be exploited in organic synthesis. 2 For …
Recent applications of the hetero Diels–Alder reaction in the total synthesis of natural products
The synthetic utility and potential power of the Diels–Alder (D–A) reaction in organic
chemistry is evident. These significances have been extended to the synthesis of a plethora …
chemistry is evident. These significances have been extended to the synthesis of a plethora …
Convergent Strategies for Syntheses of trans-Fused Polycyclic Ethers
M Inoue - Chemical reviews, 2005 - ACS Publications
The trans-fused polycyclic ethers are one of the most characteristic and spectacular classes
of compounds isolated from marine sources. These molecules are produced by marine …
of compounds isolated from marine sources. These molecules are produced by marine …
Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions
Let's talk about six! A new chiral disulfonimide catalyzed vinylogous Mukaiyama aldol
addition of crotonic acid derived nucleophiles to aldehydes has been developed and the …
addition of crotonic acid derived nucleophiles to aldehydes has been developed and the …
Selective monodeprotection of bis-silyl ethers
RD Crouch - Tetrahedron, 2004 - Elsevier
As synthetic targets have grown more complex, protection/deprotection protocols have
assumed prominent roles in synthetic organic chemistry. 1–3 The ability to efficiently protect …
assumed prominent roles in synthetic organic chemistry. 1–3 The ability to efficiently protect …