Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation

KC Nicolaou, SA Snyder - Angewandte Chemie International …, 2005 - Wiley Online Library
Over the course of the past half century, the structural elucidation of unknown natural
products has undergone a tremendous revolution. Before World War II, a chemist would …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2004 - pubs.rsc.org
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …

The modified Julia olefination: alkene synthesis via the condensation of metallated heteroarylalkylsulfones with carbonyl compounds

PR Blakemore - Journal of the Chemical Society, Perkin Transactions …, 2002 - pubs.rsc.org
reductive elimination of the β-acyloxysulfone 4 with a single electron donor to afford alkene
products. All four steps can be carried out in a single reaction vessel, although in practice …

Total synthesis of oxacyclic macrodiolide natural products

EJ Kang, E Lee - Chemical reviews, 2005 - ACS Publications
Nature presents us countless numbers of natural products with complex and fascinating
structures and useful properties. Macrodiolides belong to one relatively small but interesting …

“K‐synthesis”: recent advancements in natural product synthesis enabled by unique methods and strategies development in Korea

S Han - Bulletin of the Korean Chemical Society, 2023 - Wiley Online Library
Natural product synthesis has lain at the heart of organic chemistry. Complex structures of
natural products have inspired chemists to develop new methods and strategies. The utility …

Advances in radical conjugate additions

GSC Srikanth, SL Castle - Tetrahedron, 2005 - Elsevier
Although radicals are usually viewed as neutral, relatively nonpolar species, polar effects in
radical chemistry are wellknown 1 and continue to be exploited in organic synthesis. 2 For …

Recent applications of the hetero Diels–Alder reaction in the total synthesis of natural products

MM Heravi, T Ahmadi, M Ghavidel, B Heidari… - RSC advances, 2015 - pubs.rsc.org
The synthetic utility and potential power of the Diels–Alder (D–A) reaction in organic
chemistry is evident. These significances have been extended to the synthesis of a plethora …

Convergent Strategies for Syntheses of trans-Fused Polycyclic Ethers

M Inoue - Chemical reviews, 2005 - ACS Publications
The trans-fused polycyclic ethers are one of the most characteristic and spectacular classes
of compounds isolated from marine sources. These molecules are produced by marine …

Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions

L Ratjen, P García‐García, F Lay, ME Beck… - Angewandte Chemie …, 2011 - infona.pl
Let's talk about six! A new chiral disulfonimide catalyzed vinylogous Mukaiyama aldol
addition of crotonic acid derived nucleophiles to aldehydes has been developed and the …

Selective monodeprotection of bis-silyl ethers

RD Crouch - Tetrahedron, 2004 - Elsevier
As synthetic targets have grown more complex, protection/deprotection protocols have
assumed prominent roles in synthetic organic chemistry. 1–3 The ability to efficiently protect …