Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …

Hydrophilic interaction chromatography (HILIC) is a rapidly developing liquid
chromatography mode suitable for separation of strongly or moderately polar samples on …

Flavonoids have elicited significant attention as a result of their importance in plants, their
influence on the properties of natural-product derived commodities and especially as a …

Online comprehensive two-dimensional liquid chromatography (LC× LC) offers ways to
achieve high-performance separations in terms of peak capacity (exceeding 1000) and …

Comprehensive two-dimensional liquid chromatography represents a valuable and powerful
tool for the analysis of very complex samples. This review article illustrates how the coupling …

Cyclopia subternata plants are traditionally used for the production of the South African
herbal tea, honeybush, and recently as aqueous extracts for the food industry. A C …

The outstanding selectivity and sensitivity of specific comprehensive two-dimensional
chromatography (C2DC) methodologies (particularly with mass-spectrometry detection) …

On‐line comprehensive two‐dimensional liquid chromatography is a powerful technique for
the separation of highly complex samples. Due to the addition of the second dimension of …

Highlights•Recent LC–MS and GC–MS methods are reviewed.•The use of multiple columns
extends the coverage of the metabolome.•Super critical fluid chromatography (SFC) could …

Risk factors of type 2 diabetes mellitus (T2D) and cardiovascular disease (CVD) cluster
together and are termed the metabolic syndrome. Key factors driving the metabolic …