Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Graphene in nanomedicine: A review on nano-bio factors and antibacterial activity

S Bhatt, VD Punetha, R Pathak, M Punetha - Colloids and Surfaces B …, 2023 - Elsevier
Graphene-based nanomaterials possess potent antibacterial activity and have engrossed
immense interest among researchers as an active armour against pathogenic microbes. A …

Assessment of anticancer, antimicrobial, antidiabetic, anti-obesity and antioxidant activity of Ocimum Basilicum seeds essential oil from Palestine

AM Eid, N Jaradat, N Shraim, M Hawash, L Issa… - … Medicine and Therapies, 2023 - Springer
Background Many modern pharmaceutical researchers continue to focus on the discovery
and evaluation of natural compounds for possible therapies for obesity, diabetes, infections …

The Challenge of overcoming antibiotic resistance in carbapenem-resistant Gram-negative bacteria:“Attack on Titan”

G Mancuso, S De Gaetano, A Midiri, S Zummo… - Microorganisms, 2023 - mdpi.com
The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

Antibiotic adjuvants: Synergistic tool to combat multi-drug resistant pathogens

V Kumar, N Yasmeen, A Pandey… - Frontiers in Cellular …, 2023 - frontiersin.org
The rise of multi-drug resistant (MDR) pathogens poses a significant challenge to the field of
infectious disease treatment. To overcome this problem, novel strategies are being explored …

Chemical insights into oxidative and nitrative modifications of DNA

CMC Andrés, JMP Lastra, CA Juan, FJ Plou… - International Journal of …, 2023 - mdpi.com
This review focuses on DNA damage caused by a variety of oxidizing, alkylating, and
nitrating species, and it may play an important role in the pathophysiology of inflammation …

Bifunctional imidazolium linked tetraphenylethene based conjugated microporous polymers for dynamic antibacterial properties and supercapacitor electrodes

AO Mousa, ZI Lin, SV Chaganti, CH Chuang… - Polymer …, 2024 - pubs.rsc.org
Conjugated microporous polymers (CMPs) present intriguing potential for a myriad of
applications. In this study, we detail the synthesis of bimine-linked conjugated microporous …

Inverse association between the existence of CRISPR/Cas systems with antibiotic resistance, extended spectrum β-lactamase and carbapenemase production in …

NA Jwair, MTS Al-Ouqaili, F Al-Marzooq - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance, with the production of extended-spectrum β-lactamases (ESBL)
and carbapenemases, is common in the opportunistic pathogen, Klebsiella pneumoniae …

The role of five-membered heterocycles in the molecular structure of antibacterial drugs used in therapy

A Rusu, IM Moga, L Uncu, G Hancu - Pharmaceutics, 2023 - mdpi.com
Five-membered heterocycles are essential structural components in various antibacterial
drugs; the physicochemical properties of a five-membered heterocycle can play a crucial …

Prevalence of Salmonella Typhimurium and Salmonella Enteritidis isolated from poultry meat: virulence and antimicrobial-resistant genes

M Nazari Moghadam, E Rahimi, A Shakerian… - BMC microbiology, 2023 - Springer
Salmonellosis, a zoonotic disease, is one of the leading causes of foodborne illness
worldwide. It is responsible for most infections caused by consumption of contaminated food …