Fluorescent biosensors for neurotransmission and neuromodulation: engineering and applications

AV Leopold, DM Shcherbakova… - Frontiers in cellular …, 2019 - frontiersin.org
Understanding how neuronal activity patterns in the brain correlate with complex behavior is
one of the primary goals of modern neuroscience. Chemical transmission is the major way of …

Deep learning approaches for neural decoding across architectures and recording modalities

JA Livezey, JI Glaser - Briefings in bioinformatics, 2021 - academic.oup.com
Decoding behavior, perception or cognitive state directly from neural signals is critical for
brain–computer interface research and an important tool for systems neuroscience. In the …

Distributed and localized dynamics emerge in the mouse neocortex during reach-to-grasp behavior

E Quarta, A Scaglione, J Lucchesi… - Journal of …, 2022 - Soc Neuroscience
A long-standing question in systems neuroscience is to what extent task-relevant features of
neocortical processing are localized or distributed. Coordinated activity across the neocortex …

Miniature structured illumination microscope for in vivo 3D imaging of brain structures with optical sectioning

OD Supekar, A Sias, SR Hansen, G Martinez… - Biomedical Optics …, 2022 - opg.optica.org
We present a high-resolution miniature, light-weight fluorescence microscope with
electrowetting lens and onboard CMOS for high resolution volumetric imaging and …

Identification of thrombopoiesis inducer based on a hybrid deep neural network model

Q Mo, T Zhang, J Wu, L Wang, J Luo - Thrombosis Research, 2023 - Elsevier
Thrombocytopenia is a common haematological problem worldwide. Currently, there are no
relatively safe and effective agents for the treatment of thrombocytopenia. To address this …

Fpga-based in-vivo calcium image decoding for closed-loop feedback applications

Z Chen, GJ Blair, C Cao, J Zhou… - IEEE transactions on …, 2023 - ieeexplore.ieee.org
Miniaturized calcium imaging is an emerging neural recording technique that has been
widely used for monitoring neural activity on a large scale at a specific brain region of rats or …

Intracortical Hindlimb Brain–Computer Interface Systems: A Systematic Review

MT Ghodrati, A Mirfathollahi, V Shalchyan… - IEEE Access, 2023 - ieeexplore.ieee.org
Brain-computer interfaces (BCI) can help people with motor disorders to regain their ability
to communicate and interact with the surrounding environment. The majority of studies in …

Decoding multi-limb movements from two-photon calcium imaging of neuronal activity using deep learning

S Park, M Lipton, MC Dadarlat - Journal of Neural Engineering, 2024 - iopscience.iop.org
Objective. Brain–machine interfaces (BMIs) aim to restore sensorimotor function to
individuals suffering from neural injury and disease. A critical step in implementing a BMI is …

A convolutional autoencoder for identification of mild traumatic brain injury

F Koochaki, L Najafizadeh - 2021 10th International IEEE …, 2021 - ieeexplore.ieee.org
Mild traumatic brain injury (mTBI) is the most common form of traumatic brain injury (TBI), yet
its timely diagnosis has remained challenging due to lack of established criteria and …

End-to-end deep learning approach to mouse behavior classification from cortex-wide calcium imaging

T Ajioka, N Nakai, O Yamashita… - PLOS Computational …, 2024 - journals.plos.org
Deep learning is a powerful tool for neural decoding, broadly applied to systems
neuroscience and clinical studies. Interpretable and transparent models that can explain …