Enterocyte fatty acid-binding proteins (FABPs): different functions of liver and intestinal FABPs in the intestine

AM Gajda, J Storch - Prostaglandins, Leukotrienes and Essential Fatty …, 2015 - Elsevier
Fatty acid-binding proteins (FABP) are highly abundant cytosolic proteins that are expressed
in most mammalian tissues. In the intestinal enterocyte, both liver-(LFABP; FABP1) and …

Intestinal plasticity and metabolism as regulators of organismal energy homeostasis

O Stojanović, I Miguel-Aliaga, M Trajkovski - Nature metabolism, 2022 - nature.com
The small intestine displays marked anatomical and functional plasticity that includes
adaptive alterations in adult gut morphology, enteroendocrine cell profile and their hormone …

Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states

MK Badman, P Pissios, AR Kennedy, G Koukos… - Cell metabolism, 2007 - cell.com
Mice fed a high-fat, low-carbohydrate ketogenic diet (KD) exhibit marked changes in hepatic
metabolism and energy homeostasis. Here, we identify liver-derived fibroblast growth factor …

Hypertrophy and/or hyperplasia: dynamics of adipose tissue growth

J Jo, O Gavrilova, S Pack, W Jou, S Mullen… - PLoS computational …, 2009 - journals.plos.org
Adipose tissue grows by two mechanisms: hyperplasia (cell number increase) and
hypertrophy (cell size increase). Genetics and diet affect the relative contributions of these …

High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine

J Tomas, C Mulet, A Saffarian… - Proceedings of the …, 2016 - National Acad Sciences
Diet is among the most important factors contributing to intestinal homeostasis, and basic
functions performed by the small intestine need to be tightly preserved to maintain health …

New insights into the role of dietary triglyceride absorption in obesity and metabolic diseases

X Li, Q Liu, Y Pan, S Chen, Y Zhao, Y Hu - Frontiers in Pharmacology, 2023 - frontiersin.org
The incidence of obesity and associated metabolic diseases is increasing globally,
adversely affecting human health. Dietary fats, especially triglycerides, are an important …

The role of I-FABP as a biomarker of intestinal barrier dysfunction driven by gut microbiota changes in obesity

E Lau, C Marques, D Pestana, M Santoalha… - Nutrition & …, 2016 - Springer
Background Intestinal fatty-acid binding protein (I-FABP) is expressed in epithelial cells of
the mucosal layer of the small intestine tissue. When intestinal mucosal damage occurs, I …

Obesogen effects after perinatal exposure of 4, 4′-sulfonyldiphenol (Bisphenol S) in C57BL/6 mice

LI Del Moral, L Le Corre, H Poirier, I Niot, T Truntzer… - Toxicology, 2016 - Elsevier
Bisphenol A were removed from consumer products and replaced by chemical substitutes
such as Bisphenol S (BPS). Based on their structural similarity, BPS may be obesogen like …

Jejunum: The understudied meeting place of dietary lipids and the microbiota

I Lema, JR Araújo, N Rolhion, S Demignot - Biochimie, 2020 - Elsevier
Although the jejunum is the main intestinal compartment responsible for lipid digestion and
absorption, most of the studies assessing the impact of dietary lipids on the intestinal …

CD36 as a lipid sensor

C Martin, M Chevrot, H Poirier, P Passilly-Degrace… - Physiology & …, 2011 - Elsevier
CD36 is a multifunctional protein homologous to the class B scavenger receptor SR-B1
mainly found in tissues with a sustained lipid metabolism and in several hematopoieic cells …