Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations

F Jeanneret, D Tonoli, MF Rossier, M Saugy… - … of Chromatography A, 2016 - Elsevier
This review presents the evolution of steroid analytical techniques, including gas
chromatography coupled to mass spectrometry (GC–MS), immunoassay (IA) and targeted …

Online in-tube solid-phase microextraction coupled with liquid chromatography–tandem mass spectrometry for automated analysis of four sulfated steroid metabolites …

H Kataoka, D Nakayama - Molecules, 2022 - mdpi.com
Accurate measurement of sulfated steroid metabolite concentrations can not only enable the
elucidation of the mechanisms regulating steroid metabolism, but also lead to the diagnosis …

Parent and conjugated estrogens and progestagens in surface water of the Santa Ana River: Determination, occurrence, and risk assessment

L Ma, SR Yates, D Ashworth - Environmental toxicology and …, 2016 - Wiley Online Library
The present study investigated the occurrence of 13 parent and conjugated estrogens and
progestagens in surface water of the Santa Ana River. With the exception of the synthetic …

Gas chromatography− mass spectrometry analysis of non‐hydrolyzed sulfated steroids by degradation product formation

M Polet, W Van Gansbeke… - Drug testing and …, 2019 - Wiley Online Library
Steroid detection and identification remain key issues in toxicology, drug testing, medical
diagnostics, food safety control, and doping control. In this study, we evaluate the …

Rapid diagnosis of IDH1-mutated gliomas by 2-HG detection with gas chromatography mass spectrometry

H Xu, YK Xia, CJ Li, JY Zhang, Y Liu, W Yi… - Laboratory …, 2019 - nature.com
The metabolic genes encoding isocitrate dehydrogenase (IDH1, 2) are frequently mutated in
gliomas. Mutation of IDH defines a distinct subtype of glioma and predicts therapeutic …

High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency [S]

A Sánchez-Guijo, V Oji, MF Hartmann… - Journal of Lipid …, 2015 - ASBMB
Steroid sulfatase (STS) deficiency is the underlying cause of the skin condition known as
recessive X-linked ichthyosis (RXLI). RXLI patients show scales on their skin caused by high …

Design and evaluation of a gas chromatograph-atmospheric pressure chemical ionization interface for an exactive orbitrap mass spectrometer

JB Powers, SR Campagna - Journal of The American Society for …, 2019 - ACS Publications
Various separation and mass spectrometric (MS) techniques have furthered our ability to
study complex mixtures, and the desire to measure every analyte in a system is of continual …

Dual processing of sulfated steroids in the olfactory system of an anuran amphibian

A Sansone, T Hassenklöver, T Offner, X Fu… - Frontiers in cellular …, 2015 - frontiersin.org
Chemical communication is widespread in amphibians, but if compared to later diverging
tetrapods the available functional data is limited. The existing information on the …

High-energy collision-induced dissociation by MALDI TOF/TOF causes charge-remote fragmentation of steroid sulfates

Y Yan, M Ubukata, RB Cody, TE Holy… - Journal of The …, 2014 - ACS Publications
A method for structural elucidation of biomolecules dating to the 1980s utilized high-energy
collisions (~ 10 keV, laboratory frame) that induced charge-remote fragmentations (CRF), a …

A binary matrix for the rapid detection and characterization of small-molecule cardiovascular drugs by MALDI-MS and MS/MS

J Dong, W Ning, DJ Mans, JD Mans - Analytical Methods, 2018 - pubs.rsc.org
A mixture of α-cyano-4-hydroxycinnamic acid and 1, 5-diaminonaphthalene was discovered
as a novel binary matrix for the qualitative analysis of 14 small-molecule (∼ 250–550 Da) …