Cancer is a major public health problem around the world. Currently, about 5% of women
diagnosed with cancer are of reproductive age. These young survivors may face …

Fertility preservation is an emerging discipline, which is of substantial clinical value in the
care of young patients with cancer. Chemotherapy and radiation may induce ovarian …

The gonadotoxic effects of chemotherapy and radiation may result in premature ovarian
failure in premenopausal oncology patients. Although autotransplantation of ovarian tissue …

Introduction Neoadjuvant endocrine therapy (NET) has demonstrated efficacy in post-
menopausal patients with hormone-responsive breast cancer. This trial was designed to …

To evaluate the incidence of chemotherapy-induced amenorrhea (CIA) and its therapeutic
impact in premenopausal breast cancer patients. A systematic search was performed to …

A growing number of young breast cancer survivors consider reproductive health issues,
including subsequent fertility and pregnancy, of great importance, but many questions …

Breast cancer is the most common malignancy in women worldwide, and ovarian cancer is
the most lethal gynecological malignancy. Women carrying a BRCA1/2 mutation have a very …

Cytotoxic chemotherapy may variably affect ovarian function depending on age and ovarian
reserve at diagnosis, type of chemotherapy and use of tamoxifen. Ascertaining whether a …

Background Despite significant advances in breast cancer control and survival with
endocrine therapies (ETs), treatment utilization and outcomes in developing countries have …

Purpose To determine the likelihood of long-term amenorrhea after treatment with
chemotherapy in women with breast cancer who carry a BRCA1 or BRCA2 mutation …