KCNMA1-linked channelopathy

CS Bailey, HJ Moldenhauer, SM Park… - Journal of General …, 2019 - rupress.org
KCNMA1 encodes the pore-forming α subunit of the “Big K+”(BK) large conductance calcium
and voltage-activated K+ channel. BK channels are widely distributed across tissues …

Aminopyridines for the treatment of neurologic disorders

M Strupp, J Teufel, A Zwergal, R Schniepp… - Neurology: Clinical …, 2017 - AAN Enterprises
Purpose of review: To identify the different indications for the treatment of neurologic
disorders with the potassium channel blockers 4-aminopyridine (4-AP) and 3, 4 …

Treatment of cerebellar ataxia

TM Jones, JD Shaw, K Sullivan… - Neurodegenerative …, 2014 - Taylor & Francis
Symptoms of cerebellar degeneration include ataxia or wide-based gait, visual and speech
dysfunction, dysmetria, and dyscoordination. The etiology of cerebellar degeneration is vast …

Brain edema formation and functional outcome after surgical decompression in murine closed head injury are modulated by acetazolamide administration

J Szczygielski, V Hubertus, E Kruchten, A Müller… - Frontiers in …, 2019 - frontiersin.org
Acetazolamide (ACZ), carbonic anhydrase inhibitor, has been successfully applied in
several neurosurgical conditions for diagnostic or therapeutic purposes. Furthermore …

Effect of 4-AP on MPP+/MPTP-induced Parkinson's disease model

Q Rong, C Zhou, Y Ma - Cellular and Molecular Biology, 2023 - mail.cellmolbiol.org
To study the effect of 4-AP on Parkinson's disease (PD) cells and animal model. PD cells
were pretreated with different concentrations of 4-AP for 24 hours, then PD cells were …

[HTML][HTML] 大鼠小脑浦肯野神经元发育过程中NaV 亚基表达与电生理特性的发育成熟具有相关性

傅鸣宇, 纪晓宏, 钟磊, 吴琼, 李海福… - Journal of Southern …, 2023 - ncbi.nlm.nih.gov
大鼠小脑浦肯野神经元发育过程中NaV亚基表达与电生理特性的发育成熟具有相关性- PMC Back
to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

[引用][C] 大鼠小脑浦肯野大鼠小脑浦肯野神经元发育过程中神经元发育过程中NaV 亚基表达与电生理特性的发育成熟具有相关的发育成熟具有相关性

傅鸣宇, 纪晓宏, 钟磊, 吴琼, 李海福, 王宁黔 - europepmc.org
目的通过免疫组化和电生理记录来探讨大鼠小脑浦肯野神经元发育过程中电压门控钠通道亚基
的表达差异特性及其与电生理特性发育成熟的相关关系. 方法将大鼠根据发育阶段分为4 组 …