The Transforming Growth Factor-beta (TGF-β) family plays relevant roles in the regulation of
different cellular processes that are essential for tissue and organ homeostasis. In the case …

Cancer cells adapt to varying stress conditions to survive through plasticity. Stem cells
exhibit a high degree of plasticity, allowing them to generate more stem cells or differentiate …

Abstract Ethnopharmacological relevance Astragali Radix (AR), the root of Astragalus
membranaceus (Fisch.) Bge. or Astragalus membranaceus (Fisch.) Bge. var. mongholicus …

Therapeutic attempts to treat hepatocellular carcinoma (HCC) frequently result in a poor
response or treatment failure. The efficacy of approved drugs and survival expectancies is …

Abstract Caveolin-1 (CAV1) is commonly considered to function as a cell surface protein, for
instance in the genesis of caveolae. Nonetheless, it is also present in many intracellular …

Liver cancer represents a major health problem worldwide with growing incidence and high
mortality, hepatocellular carcinoma (HCC) being the most frequent. Hepatocytes are likely …

Simple Summary Transforming growth factor β (TGF-β) signaling is a preeminent regulator
of diverse cellular and physiological processes. Frequent dysregulation of TGF-β signaling …

Stress-induced premature cellular senescence is a significant factor in the onset of age-
dependent disease in the cardiovascular system. Plasminogen activator inhibitor-1 (PAI-1) …

Introduction: Hydrogel nanoparticles, also known as nanogels (NGs), have been recently
proposed as alternative supramolecular vehicles for the delivery of biologically relevant …

Hepatocellular carcinoma (HCC) is the major form of primary liver cancer and one of the
most prevalent and life-threatening malignancies globally. One of the hallmarks in HCC is …