Differential expression of the immediate early genes c-Fos, Arc, Egr-1, and Npas4 during long-term memory formation in the context preexposure facilitation effect …

NA Heroux, BF Osborne, LA Miller, M Kawan… - Neurobiology of learning …, 2018 - Elsevier
The context preexposure facilitation effect (CPFE) is a contextual fear conditioning paradigm
in which learning about the context, acquiring the context-shock association, and …

Differential involvement of the medial prefrontal cortex across variants of contextual fear conditioning

NA Heroux, PA Robinson-Drummer… - Learning & …, 2017 - learnmem.cshlp.org
The context preexposure facilitation effect (CPFE) is a contextual fear conditioning paradigm
in which learning about the context, acquiring the context-shock association, and …

Egr-1 increases in the prefrontal cortex following training in the context preexposure facilitation effect (CPFE) paradigm

A Asok, WB Schreiber, SA Jablonski, JB Rosen… - Neurobiology of learning …, 2013 - Elsevier
The context pre-exposure facilitation effect (CPFE) is a modified form of standard contextual
fear conditioning that dissociates learning about the context during a preexposure phase …

Neonatal ethanol exposure impairs trace fear conditioning and alters NMDA receptor subunit expression in adult male and female rats

MJ Goodfellow, KA Abdulla… - Alcoholism: Clinical and …, 2016 - Wiley Online Library
Background Ethanol (EtOH) exposure in neonate rats during a period comparable to the
human third trimester, postnatal days (PD) 4 to 9, leads to persistent deficits in forebrain …

Using the context preexposure facilitation effect to study long-term context memory in preweanling, juvenile, adolescent, and adult rats

PA Robinson-Drummer, ME Stanton - Physiology & behavior, 2015 - Elsevier
The present study used the context preexposure facilitation effect (CPFE) to examine long-
term retention of incidental context learning in periweanling, adolescent and adult rats. The …

Early developmental alcohol exposure alters behavioral outcomes following adolescent re‐exposure in a rat model

RD Risbud, KR Breit, JD Thomas - Alcoholism: Clinical and …, 2022 - Wiley Online Library
Background Prenatal alcohol exposure alters brain development, affecting cognitive, motor,
and emotional domains, and potentially leading to greater alcohol intake during …

Neonatal ethanol causes profound reduction of cholinergic cell number in the basal forebrain of adult animals

JF Smiley, C Bleiwas, S Canals-Baker, SZ Williams… - Alcohol, 2021 - Elsevier
In animal models that mimic human third-trimester fetal development, ethanol causes
substantial cellular apoptosis in the brain, but for most brain structures, the extent of …

Neonatal ethanol exposure impairs long-term context memory formation and prefrontal immediate early gene expression in adolescent rats

NA Heroux, PA Robinson-Drummer, M Kawan… - Behavioural brain …, 2019 - Elsevier
Fetal alcohol exposure leads to severe disruptions in learning and memory involving the
hippocampus and prefrontal cortex in humans. Animal model research on FASD has …

Neonatal infection produces significant changes in immune function with no associated learning deficits in juvenile rats

BF Osborne, JI Caulfield, SA Solomotis… - Developmental …, 2017 - Wiley Online Library
The current experiments examined the impact of early‐life immune activation and a
subsequent mild immune challenge with lipopolysaccharide (LPS; 25µg/kg) on hippocampal …

Antagonism of muscarinic acetylcholine receptors in medial prefrontal cortex disrupts the context preexposure facilitation effect

PA Robinson-Drummer, NA Heroux… - Neurobiology of Learning …, 2017 - Elsevier
Cholinergic function plays a role in a variant of context fear conditioning known as the
context preexposure facilitation effect (CPFE; Robinson-Drummer, Dokovna, Heroux, & …