Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …

The prevalence of obesity is increasing and progressively influencing physician‐patient
interactions. While there is a sizable amount of data demonstrating that obesity is a state of …

IL (interleukin)-6, which was originally identified as a B-cell differentiation factor, is a
multifunctional cytokine that regulates the immune response, haemopoiesis, the acute …

ContextHuman adipose tissue expresses and releases the proinflammatory cytokine
interleukin 6, potentially inducing low-grade systemic inflammation in persons with excess …

Obesity may be a low-grade systemic inflammatory disease. Overweight and obese children
and adults have elevated serum levels of C-reactive protein, interleukin-6, tumor necrosis …

Objectives: To explore the links between tumor necrosis factor α (TNFα) and leptin adipose
tissue expression and low‐grade systemic inflammation and to determine the relationship …

Sepsis is a major clinical problem for which therapeutic interventions have been largely
unsuccessful, in spite of promising strategies that were successful in animals, especially …

Objective. Human adipose tissue expresses and releases the proinflammatory cytokine
interleukin-6, potentially inducing low-grade systemic inflammation in persons with excess …

For about half a century, the binding of drugs to plasma albumin, the “silent receptor,” has
been recognized as one of the major determinants of drug action, distribution, and …

Obesity and the metabolic syndrome have both reached pandemic proportions. Together
they have the potential to impact on the incidence and severity of cardiovascular …