DNA damage and repair in human reproductive cells

A García-Rodríguez, J Gosálvez, A Agarwal… - International Journal of …, 2018 - mdpi.com
The fundamental underlying paradigm of sexual reproduction is the production of male and
female gametes of sufficient genetic difference and quality that, following syngamy, they …

Sperm selection in assisted reproduction: A review of established methods and cutting-edge possibilities

G Marzano, MS Chiriacò, E Primiceri… - Biotechnology …, 2020 - Elsevier
Male infertility often involves idiopathic or unknown causes, leading to an increasing
demand for assisted reproduction technologies (ART). Conventional sperm sorting …

Telomere length: lights and shadows on their role in human reproduction

MS Rocca, C Foresta, A Ferlin - Biology of Reproduction, 2019 - academic.oup.com
Telomeres are repeated DNA sequences whose main function is to preserve genome
stability, protecting chromosomes ends from shortening caused by progressive loss during …

The association of female and male infertility with telomere length

E Vasilopoulos, P Fragkiadaki… - International …, 2019 - spandidos-publications.com
Telomere length (TL) has long been associated with aging, as telomeres serve as protective
caps of chromosomes, and are thus deeply involved in the preservation of genome integrity …

[PDF][PDF] Sperm telomere length as a parameter of sperm quality in normozoospermic men

MS Rocca, E Speltra, M Menegazzo… - Human …, 2016 - scholar.archive.org
The evaluation of male (in) fertility is commonly based on standard semen analysis, which,
however, cannot clearly distinguish fertile from infertile populations and fails to detect any …

Sperm telomere length as a novel biomarker of male infertility and embryonic development: A systematic review and meta-analysis

Y Yuan, Y Tan, X Qiu, H Luo, Y Li, R Li… - Frontiers in …, 2023 - frontiersin.org
Background Telomeres have an essential role in maintaining the integrity and stability of the
human chromosomal genome and preserving essential DNA biological functions. Several …

The paternal age at conception effect on offspring telomere length: mechanistic, comparative and adaptive perspectives

DTA Eisenberg, CW Kuzawa - … Transactions of the …, 2018 - royalsocietypublishing.org
Telomeres are repeating DNA found at the ends of chromosomes that, in the absence of
restorative processes, shorten with cell replications and are implicated as a cause of …

Oxidative stress and reproductive function: Sperm telomeres, oxidative stress, and infertility

A Moazamian, P Gharagozloo, RJ Aitken… - …, 2022 - rep.bioscientifica.com
In brief Oxidative stress is recognized as an underlying driving factor of both telomere
dysfunction and human subfertility/infertility. This review briefly reassesses telomere integrity …

Investigation of sperm telomere length as a potential marker of paternal genome integrity and semen quality

F Cariati, S Jaroudi, S Alfarawati, A Raberi… - Reproductive …, 2016 - Elsevier
Recent studies have reported shorter sperm telomere length (STL) in men with idiopathic
infertility. The aim of this study was to measure STL in semen samples from men to evaluate …

Sperm selection strategies and their impact on assisted reproductive technology outcomes

S Pinto, DF Carrageta, MG Alves, A Rocha… - Andrologia, 2021 - Wiley Online Library
The application of assisted reproductive technologies (ART) has revolutionised the
treatment of human infertility, giving hope to the patients previously considered incapable of …