Understanding the physical and chemical nature of the warfarin drug binding site in human serum albumin: experimental and theoretical studies

O K. Abou-Zied - Current Pharmaceutical Design, 2015 - benthamdirect.com
Human serum albumin (HSA) is one of the major carrier proteins in the body and constitutes
approximately half of the protein found in blood plasma. It plays an important role in lipid …

Cucurbit [n] uril Host‐Guest Complexes of Acids, Photoacids, and Super Photoacids

DH Macartney - Israel Journal of Chemistry, 2018 - Wiley Online Library
The supramolecular chemistry of host‐guest complexes of cucurbit [n] urils (CB [n]) with
acidic guests in the ground (HG+) and excited states (HG+*) are reviewed. The effects of CB …

A Cucurbit[8]uril 2:2 Complex with a Negative pKa Shift

H Yin, Q Cheng, R Rosas, S Viel… - … A European Journal, 2019 - Wiley Online Library
A viologen derivative carrying a benzimidazole group (V‐P‐I 2+; viologen–phenylene–
imidazole V‐P‐I) can be dimerized in water using cucurbit [8] uril (CB [8]) in the form of a 2: 2 …

Simultaneous binding of folic acid and methotrexate to human serum albumin: insights into the structural changes of protein and the location and competitive …

S Panja, DK Khatua, M Halder - ACS omega, 2018 - ACS Publications
Protein structure can be flexible to adopt multiple conformations to house small molecules.
In this paper, we have attempted to experimentally figure out how the structure of a transport …

Analytical aspects of achiral and cyclodextrin-mediated capillary electrophoresis of warfarin and its two main derivatives assisted by theoretical modeling

P Nowak, M Garnysz, MP Mitoraj, F Sagan… - … of Chromatography A, 2015 - Elsevier
Several distinct analytical issues have been addressed by performing capillary
electrophoresis-based separations of the warfarin, 7-hydroxywarfarin and 10 …

Modulation of p K a by cyclodextrins; subtle structural changes induce spectacularly different behaviors

PM Nowak, M Woźniakiewicz, MP Mitoraj, M Garnysz… - RSC …, 2015 - pubs.rsc.org
Tuning of acidity-related properties by host–guest complexation is one of the most promising
concepts in current supramolecular chemistry. However, still little is known about structural …

Acidity constant of pH indicators in the supramolecular systems studied by two CE-based methods compared using the RGB additive color model

PM Nowak, P Leszczenko, J Zarusińska… - Analytical and …, 2020 - Springer
Acid-base properties of methyl orange, bromocresol green, bromophenol blue, and
bromothymol blue were thoroughly investigated in the past due to their application as …

Optical spectroscopic and morphological characterizations of curcuminized silk biomaterials: a perspective from drug stabilization

S Panja, S Behera, SC Kundu, M Halder - Acs Omega, 2017 - ACS Publications
Silk protein fibroins have gained remarkable attention in recent years as a potential drug
carrier in the developing medicinal field of research. In this work, the stability of anticancer …

Distilbene derivative as a new environment-sensitive bifunctional ligand for the possible induction of serum protein aggregation: a spectroscopic Investigation and …

S Datta, S Panja, P Mitra, M Halder - Langmuir, 2015 - ACS Publications
The photophysical properties of a new distilbene fluorophore, DPDB, belonging to the
conjugated polyene family is found to be well modulated with the variation of the …

A comparative study of various physicochemically modified capillaries used in CE technique for the three distinct analytical purposes

PM Nowak, M Woźniakiewicz, M Garnysz… - … of Chromatography B, 2016 - Elsevier
The five different commercially offered capillaries, bare silica, one dynamically and three
permanently coated, have been tested with respect to the three distinct bioanalytical …