Novel targets in deep brain stimulation for movement disorders

AJ Baumgartner, JA Thompson, DS Kern… - Neurosurgical …, 2022 - Springer
The neurosurgical treatment of movement disorders, primarily via deep brain stimulation
(DBS), is a rapidly expanding and evolving field. Although conventional targets including the …

[HTML][HTML] Deep brain stimulation for the treatment of tremor

V Chandra, JD Hilliard, KD Foote - Journal of the neurological sciences, 2022 - Elsevier
This review article provides a brief historical perspective on the use of DBS for tremor,
reviews the various etiologies for tremor that can be effectively managed with DBS therapy …

Deep-brain stimulation for essential tremor and other tremor syndromes: A narrative review of current targets and clinical outcomes

C Iorio-Morin, A Fomenko, SK Kalia - Brain Sciences, 2020 - mdpi.com
Tremor is a prevalent symptom associated with multiple conditions, including essential
tremor (ET), Parkinson's disease (PD), multiple sclerosis (MS), stroke and trauma. The …

Deep brain stimulation in the caudal zona incerta versus best medical treatment in patients with Parkinson's disease: a randomised blinded evaluation

P Blomstedt, RS Persson, GM Hariz, J Linder… - Journal of Neurology …, 2018 - jnnp.bmj.com
Background Several open-label studies have shown good effect of deep brain stimulation
(DBS) in the caudal zona incerta (cZi) on tremor, including parkinsonian tremor, and in some …

Deep brain stimulation for tremor: Update on long-term outcomes, target considerations and future directions

NI Kremer, RWJ Pauwels, NG Pozzi, F Lange… - Journal of Clinical …, 2021 - mdpi.com
Deep brain stimulation (DBS) of the thalamic ventral intermediate nucleus is one of the main
advanced neurosurgical treatments for drug-resistant tremor. However, not every patient …

[HTML][HTML] The role of the motor thalamus in deep brain stimulation for essential tremor

C Neudorfer, K Kultas-Ilinsky, I Ilinsky, S Paschen… - …, 2024 - Elsevier
The advent of next-generation technology has significantly advanced the implementation
and delivery of Deep Brain Stimulation (DBS) for Essential Tremor (ET), yet controversies …

Improving tremor response to focused ultrasound thalamotomy

JM Holcomb, R Chopra, FS Feltrin… - Brain …, 2023 - academic.oup.com
MRI-guided high-intensity focused ultrasound thalamotomy is an incisionless therapy for
essential tremor. To reduce adverse effects, the field has migrated to treating at 2 mm above …

Advanced imaging and direct targeting of the motor thalamus and dentato-rubro-thalamic tract for tremor: a systematic review

N Gravbrot, M Saranathan, N Pouratian… - Stereotactic and …, 2020 - karger.com
Direct targeting methods for stereotactic neurosurgery in the treatment of essential tremor
have been the subject of active research over the past decade but have not yet been …

Ventral intermediate nucleus versus zona incerta region deep brain stimulation in essential tremor

RS Eisinger, J Wong, L Almeida… - Movement disorders …, 2018 - Wiley Online Library
Background The ventral intermediate nucleus (VIM) is the target of choice for Essential
Tremor (ET) deep brain stimulation (DBS). Renewed interest in caudal zona incerta (cZI) …

Surgical treatments for essential tremor

RJ Elble, L Shih, JW Cozzens - Expert review of neurotherapeutics, 2018 - Taylor & Francis
Introduction: Essential tremor is the most common form of pathologic tremor. Surgical
therapies disrupt tremorogenic oscillation in the cerebellothalamocortical pathway and are …