Roadmap for metal nanoparticles in radiation therapy: Current status, translational challenges, and future directions

J Schuemann, AF Bagley, R Berbeco… - Physics in Medicine …, 2020 - iopscience.iop.org
This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …

Monte Carlo studies in Gold Nanoparticles enhanced radiotherapy: The impact of modelled parameters in dose enhancement

E Vlastou, S Diamantopoulos, EP Efstathopoulos - Physica Medica, 2020 - Elsevier
Purpose Over the last decades, Gold Nanoparticles (AuNPs) have been presented as an
innovative approach in radiotherapy (RT) enhancement. Several studies have proven that …

[HTML][HTML] Intercomparison of Monte Carlo calculated dose enhancement ratios for gold nanoparticles irradiated by X-rays: Assessing the uncertainty and correct …

H Rabus, WB Li, C Villagrasa, J Schuemann… - Physica Medica, 2021 - Elsevier
Abstract Results of a Monte Carlo code intercomparison exercise for simulations of the dose
enhancement from a gold nanoparticle (GNP) irradiated by X-rays have been recently …

The potential role of borophene as a radiosensitizer in boron neutron capture therapy (BNCT) and particle therapy (PT)

P Qi, Q Chen, D Tu, S Yao, Y Zhang, J Wang… - Biomaterials …, 2020 - pubs.rsc.org
The potential role of borophene as a radiosensitizer in PT and BNCT was investigated. Our
study focused on two aspects:(1) the synthesis and characterization of borophene …

Energy optimization in gold nanoparticle enhanced radiation therapy

W Sung, J Schuemann - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Gold nanoparticles (GNPs) have been demonstrated as radiation dose enhancing agents.
Kilovoltage external photon beams have been shown to yield the largest enhancement due …

Monte Carlo simulation of free radical production under keV photon irradiation of gold nanoparticle aqueous solution. Part I: Global primary chemical boost

F Poignant, H Charfi, CH Chan, E Dumont… - Radiation Physics and …, 2020 - Elsevier
The use of gold nanoparticles to enhance radiation therapy efficiency has been thoroughly
investigated over the past two decades. While theoretical studies have mostly focused on …

Dosimetric consequences of gold nanoparticle clustering during photon irradiation

C Kirkby, B Koger, N Suchowerska… - Medical …, 2017 - Wiley Online Library
Purpose The radiation dose enhancement caused by introducing gold nanoparticles (GNP)
into cells can increase the dose locally absorbed. A disconnect between experimentally …

Monte Carlo investigation of the effect of gold nanoparticles' distribution on cellular dose enhancement

FS Rasouli, SF Masoudi - Radiation Physics and Chemistry, 2019 - Elsevier
Purpose In recent decades‎,‎ radiotherapy has became one of the most useful and cost
effective tools in cancer treatment‎. Having a number of unique characteristics made gold …

Impact of the spectral composition of kilovoltage x-rays on high-z nanoparticle-assisted dose enhancement

MA Kolyvanova, AV Belousov, GA Krusanov… - International Journal of …, 2021 - mdpi.com
Nanoparticles (NPs) with a high atomic number (Z) are promising radiosensitizers for cancer
therapy. However, the dependence of their efficacy on irradiation conditions is still unclear …

Estimation of dose enhancement for inhomogeneous distribution of nanoparticles: A Monte Carlo study

F Abolaban, E Taha, A Alhawsawi, F Djouider… - Applied Sciences, 2021 - mdpi.com
High atomic number nanoparticles are of increasing interest in radiotherapy due to their
significant positive impact on the local dose applied to the treatment site. In this work, three …