Neurotensin is an endogenous tridecapeptide neurotransmitter (pGlu-Leu-Tyr-Glu-Asn-Lys-
Pro-Arg-Arg-Pro-Try-Ile-Leu-OH) that was discovered by Carraway and Leeman in bovine …

Obesity and its associated comorbidities (for example, diabetes mellitus and hepatic
steatosis) contribute to approximately 2.5 million deaths annually and are among the most …

OBJECTIVE: Four studies using identical protocols evaluated the safety and efficacy of four
novel, evidence-based targets for antipsychotic agents: a neurokinin (NK3) antagonist …

A search for sequences homologous to the neurotensin receptor cDNA in a rat hypothalamic
library has identified a novel neurotensin receptor (NTR‐2). The 1539 bp cDNA encodes a …

Survival depends on an organism's ability to sense nutrient status and accordingly regulate
intake and energy expenditure behaviors. Uncoupling of energy sensing and behavior …

Neurons of the lateral hypothalamic area (LHA) control motivated behaviors such as feeding
and ambulatory activity, in part by modulating mesolimbic dopamine (DA) circuits. The …

Schizophrenia is a devastating psychiatric illness that affects approximately 1% of the world
population irrespective of ethnic, economical, or cultural boundaries: features that suggest …

The effects of interruption of dopaminergic transmission or sustained blockade of dopamine
receptors by neuroleptics on the dopamine D3 receptor in the shell of the nucleus …

More than two decades of research indicate that the peptide neurotensin (NT) and its
cognate receptors participate to a remarkable extent in the regulation of mammalian …

Neurotensin (NT), an endogenous brain–gut peptide, has a close anatomical and functional
relationship with the mesocorticolimbic and neostriatal dopamine system. Dysregulation of …