Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver tumor and
remains a fatal malignancy in the majority of patients. Approximately 20%–30% of patients …

Cholangiocarcinoma is the second most common primary liver cancer. Its incidence is low in
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …

Background & Aims Cholangiocarcinoma (CCA) is a rare and heterogeneous biliary cancer,
whose incidence and related mortality is increasing. This study investigates the clinical …

Cholangiocarcinoma (CCA) is a heterogeneous disease arising from a complex interaction
between host‐specific genetic background and multiple risk factors. Globally, CCA …

Background & Aims Intrahepatic (ICC) and extrahepatic cholangiocarcinoma (ECC) have
rarely been studied individually, probably due to difficulties in their diagnosis and …

Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most
frequently occurring types of primary liver cancer and together are among the most common …

Gut dysbiosis is commonly observed in patients with cirrhosis and chronic gastrointestinal
disorders; however, its effect on antitumor immunity in the liver is largely unknown. Here we …

Background & Aims Cholangiocarcinoma (CCA) carries a poor prognosis, is increasing in
incidence and its causes are poorly understood. Although some risk factors are known, they …

Primary liver cancer represents a major health problem. It comprises hepatocellular
carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), which differ markedly with …

Biliary tract cancer (BTC), comprising< 1% of all human cancers and∼ 10%–15% of all
primary liver cancers, presents mostly in the seventh decade with a small male …