Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of oral cancer

AS Doghish, SS Elshaer, D Fathi, NI Rizk… - … -Research and Practice, 2024 - Elsevier
Oral cancer (OC) is a widely observed neoplasm on a global scale. Over time, there has
been an increase in both its fatality and incidence rates. Oral cancer metastasis is a complex …

Emerging biomarkers for non-invasive diagnosis and treatment of cancer: a systematic review

S Zakari, NK Niels, GV Olagunju, PC Nnaji… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Cancer remains a global health challenge, necessitating continuous advancements in
diagnostic and treatment strategies. This review focuses on the utility of non-invasive …

Proteome Fishing for CRISPR/Cas12a-Based Orthogonal Multiplex Aptamer Sensing

S Li, B Jin, Y Ma, X Yang, J Fan, Y Xie… - Journal of the …, 2024 - ACS Publications
Detection of serum protein biomarkers is extremely challenging owing to the superior
complexity of serum. Here, we report a method of proteome fishing from the serum. It uses a …

[HTML][HTML] Histological Improvement and Cytokine Levels Reduction in Patients with Oral Lichen Planus after Photobiomodulation Therapy

MZ Mutafchieva, MN Draganova, GT Tomov - Biomedicines, 2024 - mdpi.com
Background: Oral lichen planus (OLP) is a mucocutaneous disease associated with the
formation of symptomatic lesions in the mouth that are often refractory to treatment. An as-yet …

[HTML][HTML] Impact of juglone, a PIN1 inhibitor, on oral carcinogenesis induced by 4-nitroquinoline-1-oxide (4NQO) in rat model

O Topal, BG Topal, Y Baş, B Ongan, G Sadi, E Aslan… - Medicina, 2024 - mdpi.com
Background and Objectives: PIN1 is overexpressed in several human cancers, including
prostate cancer, breast cancer, and oral squamous carcinomas. Juglone (J), derived from …

Salivary miRNAs as auxiliary liquid biopsy biomarkers for diagnosis in patients with oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis

H Nguyen, T Nonaka - Frontiers in Genetics, 2024 - frontiersin.org
Objective: The healthcare system needs a novel approach to improve and diagnose early
oropharyngeal squamous cell carcinoma against its low survival rate. We conduct a …

[HTML][HTML] The Role of Spirituality and Religion in Improving Quality of Life and Coping Mechanisms in Cancer Patients

DS Nagy, A Isaic, AC Motofelea, DI Popovici… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Objectives: This systematic review aimed to comprehensively evaluate the role
of spirituality and religion in the journey of patients with cancer and assess their impact on …

[HTML][HTML] Stability of circulating miRNA in saliva: The influence of sample associated pre-analytical variables

C Romani, M Baronchelli, C Assoni, D Mattavelli… - Clinica Chimica …, 2024 - Elsevier
Background and aims Increasing evidence supports the practicability of salivary cell-free (cf)
miRNA as liquid biopsy markers in cancers. Its successful translation in the clinical setting …

Impact of juglone on oral carcinogenesis induced by 4-nitroquinoline-1-oxide (4NQO) in rat model

O Topal, B Topal, Y Baş, B Ongan, G Sadi, E Aslan… - bioRxiv, 2024 - biorxiv.org
In this study, the potential effects of juglone, also known as PIN1 inhibitor, on oral cancer
and carcinogenesis were investigated at the molecular level. 4-Nitroquinoline N-oxide (4 …

[PDF][PDF] ADVANCEMENTS IN NON-INVASIVE ORAL CANCER DETECTION: UNVEILING INSIGHTS FROM CIRCULATING MIRNA PROFILING

AINNONI ORAL - 2023 - iipseries.org
Within the pages of this book chapter lies an in-depth exploration of the present status of
circulating miRNAs, illuminating their promising role in the realm of oral cancer detection …