Bladder cancer

L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature Reviews …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

Clinical therapies and nano drug delivery systems for urinary bladder cancer

P Jain, H Kathuria, M Momin - Pharmacology & Therapeutics, 2021 - Elsevier
Bladder cancer is the 10 th most commonly occurring malignancy worldwide with a 75% of 5-
year survival rate, while it ranks 13 th among the deaths occurring due to cancer. The …

Recent Advances in Transcription Factors Biomarkers and Targeted Therapies Focusing on Epithelial–Mesenchymal Transition

KT Chuang, SS Chiou, SH Hsu - Cancers, 2023 - mdpi.com
Simple Summary The study discusses the potential of targeting transcription factors (TFs) for
cancer therapy and provide a systematic classification of various types of TFs involved in the …

The androgen receptor in bladder cancer

J Chen, CP Huang, C Quan, X Zu, Z Ou… - Nature Reviews …, 2023 - nature.com
Bladder cancer is the ninth most common cancer worldwide with a striking sex-based
difference in incidence. Emerging evidence indicates that the androgen receptor (AR) might …

A network pharmacology perspective for deciphering potential mechanisms of action of Solanum nigrum L. in bladder cancer

Y Dong, L Hao, K Fang, X Han, H Yu, J Zhang… - … medicine and therapies, 2021 - Springer
Background Solanum nigrum L. decoction has been used as a folklore medicine in China to
prevent the postoperative recurrence of bladder cancer (BC). However, there are no …

The clinical significance and prognostic value of HER2 expression in bladder cancer: a meta-analysis and a bioinformatic analysis

K Gan, Y Gao, K Liu, B Xu, W Qin - Frontiers in oncology, 2021 - frontiersin.org
Objective Human Epidermal Growth Factor Receptor 2 (HER2) is highly expressed in
multiple malignancies and associated with patients' prognosis, but its role in bladder cancer …

Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer

M Mohsenzadegan, M Razmi, S Vafaei… - Scientific reports, 2022 - nature.com
Melanoma antigen gene (MAGE)-A6 and MAGE-A11 are two of the most cancer-testis
antigens overexpressed in various types of cancers. However, the clinical and prognosis …

Are androgen receptor agonists a treatment option in bladder cancer?

ML De Ieso, AF Aldoghachi, WD Tilley… - The Journal of Steroid …, 2024 - Elsevier
Sex-related differences in bladder cancer incidence and progression infer a role for sex
hormones and their cognate receptors in this disease. In part due to the oncogenic role of …

Stranger things: new roles and opportunities for androgen receptor in oncology beyond prostate cancer

J Leo, E Dondossola, KJ Basham, NR Wilson… - …, 2023 - academic.oup.com
The androgen receptor (AR) is one of the oldest therapeutic targets in oncology and
continues to dominate the treatment landscape for advanced prostate cancer, where nearly …

The role of androgens and androgen receptor in human bladder cancer

E Martínez-Rojo, LC Berumen, G García-Alcocer… - Biomolecules, 2021 - mdpi.com
Bladder cancer (urothelial carcinoma) is one of the most frequently diagnosed neoplasms,
with an estimated half a million new cases and 200,000 deaths per year worldwide. This …