Major coagulation disorders and parameters in COVID-19 patients

A Teimury, MT Khameneh, EM Khaledi - European journal of medical …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), with a high prevalence rate, has rapidly
infected millions of people around the world. Since viral infections can disrupt the …

Perioperative considerations in management of the severely bleeding coagulopathic patient

G Erdoes, D Faraoni, A Koster, ME Steiner… - Obstetric Anesthesia …, 2024 - journals.lww.com
This clinical review explored coagulopathy in severely bleeding patients after major surgery
(eg, cardiac surgery with cardiopulmonary bypass or CPB), serious trauma, and postpartum …

Argatroban versus heparin in patients without heparin-induced thrombocytopenia during venovenous extracorporeal membrane oxygenation: a propensity-score …

C Fisser, M Winkler, MV Malfertheiner, A Philipp… - Critical Care, 2021 - Springer
Background During venovenous extracorporeal membrane oxygenation (vvECMO), direct
thrombin inhibitors are considered by some potentially advantageous over unfractionated …

Combining flavin photocatalysis with parallel synthesis: a general platform to optimize peptides with non-proteinogenic amino acids

JR Immel, M Chilamari, S Bloom - Chemical Science, 2021 - pubs.rsc.org
Most peptide drugs contain non-proteinogenic amino acids (NPAAs), born out through
extensive structure–activity relationship (SAR) studies using solid-phase peptide synthesis …

[HTML][HTML] Prediction of repurposed drugs for Coronaviruses using artificial intelligence and machine learning

A Rajput, A Thakur, A Mukhopadhyay, S Kamboj… - Computational and …, 2021 - Elsevier
The world is facing the COVID-19 pandemic caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2). Likewise, other viruses of the Coronaviridae family were …

Both full-length and protease-cleaved products of osteopontin are elevated in infectious diseases

T Hattori, H Iwasaki-Hozumi, G Bai, H Chagan-Yasutan… - Biomedicines, 2021 - mdpi.com
Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …

COVID-19 and the concept of thrombo-inflammation: Review of the relationship between immune response, endothelium and coagulation

E de Maistre, P Savard, PG Guinot - Journal of Clinical Medicine, 2023 - mdpi.com
COVID-19, caused by the SARS-CoV-2 virus, has revealed a complex interplay between
inflammation and coagulation, leading to the emergence of the concept of thrombo …

Monitoring of argatroban in critically ill patients: A prospective study comparing activated partial thromboplastin time, point-of-care viscoelastic testing with ecarin …

L Heubner, R Oertel, O Tiebel… - …, 2024 - ingentaconnect.com
Background: The direct thrombin inhibitor argatroban is indicated for the treatment of
heparin-induced thrombocytopenia II, but it is also used off-label to treat critically ill patients …

Recent advance in treatment of atherosclerosis: Key targets and plaque-positioned delivery strategies

L Li, S Liu, J Tan, L Wei, D Wu, S Gao… - Journal of tissue …, 2022 - journals.sagepub.com
Atherosclerosis, a chronic inflammatory disease of vascular wall, is a progressive
pathophysiological process with lipids oxidation/depositing initiation and innate/adaptive …

Gold single atom-based aptananozyme as an ultrasensitive and selective colorimetric probe for detection of thrombin and C-reactive protein

GK Ali, FK Algethami, KM Omer - Microchimica Acta, 2024 - Springer
An ultra-efficient biocatalytic peroxidase-like Au-based single-atom nanozyme (Au-
SAzymes) has been synthesized from isolated Au atoms on black nitrogen doped carbon …