HCV core antigen plays an important role in the fight against HCV as an alternative to HCV‐RNA detection

Y Wang, W Jie, J Ling… - Journal of Clinical …, 2021 - Wiley Online Library
Objective To discuss the clinical significance of HCV‐cAg testing in the diagnosis, activity
determination, and monitoring of therapeutic effectiveness of HCV infection and its …

Hepatitis C core antigen testing: a reliable, quick, and potentially cost-effective alternative to hepatitis C polymerase chain reaction in diagnosing acute hepatitis C …

FV Cresswell, M Fisher, DJ Hughes… - Clinical Infectious …, 2015 - academic.oup.com
Hepatitis C virus (HCV) is increasingly common among human immunodeficiency virus
(HIV)-infected men who have sex with men. We evaluated the efficacy of HCV core antigen …

Indian National Association for Study of the Liver (INASL) guidance for antiviral therapy against HCV infection: update 2016

P Puri, VA Saraswat, RK Dhiman, AC Anand… - Journal of clinical and …, 2016 - Elsevier
India contributes significantly to the global burden of HCV. While the nucleoside NS5B
inhibitor sofosbuvir became available in the Indian market in March 2015, the other directly …

[PDF][PDF] Sero-prevalence of hepatitis-c virus among blood donors in northern Pakistan

S Ali, B Ali, BB Khan, M Khan, S Ali - MOJ Public Health, 2023 - researchgate.net
HCV is a hepatotropic single strained positive sense RNA virus belongs to family
Flaviviridae. HCV is worldwide distributed virus affects about 185 million peoples as a result …

Performance of ARCHITECT HCV core antigen test with specimens from US plasma donors and injecting drug users

T Mixson-Hayden, GJ Dawson, E Teshale, T Le… - Journal of clinical …, 2015 - Elsevier
Abstract Background Hepatitis C virus (HCV) core antigen is a serological marker of current
HCV infection. Objectives The aim of this study was mainly to evaluate the performance …

Utility of hepatitis C virus core antigen testing for diagnosis and treatment monitoring in HCV infection: a study from India

N Kumbhar, K Ramachandran, G Kumar… - Indian Journal of …, 2021 - Elsevier
Purpose The major bottleneck in most developing countries to attain the WHO goal of
eliminating hepatitis C as a public health threat by 2030 is the limited access to molecular …

Hepatitis C virus core antigen assay: an alternative method for hepatitis C diagnosis

L Wang, H Lv, G Zhang - Annals of clinical biochemistry, 2017 - journals.sagepub.com
Background The study aimed to evaluate a fully automated chemiluminescent immunoassay
and compared it with a quantitative RNA assay and anti-HCV assay to verify the utility of this …

Very low hepatitis C viral loads in treatment-naive persons: do they compromise hepatitis C virus antigen testing?

B Bertisch, M Brezzi, F Negro… - Clinical infectious …, 2020 - academic.oup.com
Abstract Background Hepatitis C virus (HCV) antigen testing is less expensive than
quantitative reverse-transcription polymerase chain reaction but has lower sensitivity for very …

[HTML][HTML] Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus

RN Bedair, GM Magour, SA Ooda, EM Amar… - Egyptian Liver …, 2021 - Springer
Background Insulin receptor substrate-1 (IRS1) plays a critical role in insulin signaling. IRS-
1 gene polymorphism with glycine to arginine substitution (GGG↔ AGG substitutions) in …

Detection of hepatitis C virus core antigen as an alternative method for diagnosis of hepatitis C virus infection in blood donors negative for hepatitis C virus antibody

TM Hassanin, EM Abdelraheem… - European Journal of …, 2020 - journals.lww.com
Background Screening of blood donors in many countries is based on the use of serologic
assays to detect specific anti-HCV antibodies (HCV Ab), but it lacks detection sensitivity. So …