The complement system is important for cellular integrity and tissue homeostasis.
Complement activation mediates the removal of microorganisms and the clearance of …

The relationship between infections and autoimmunity as well as the risk of infections due to
antirheumatic agents, including corticosteroids, immunosuppressants and biologics, are …

Decoding Cell Death Signals in Inflammation and Immunity: Cell Skip to Main Content
Advertisement Cell This journal offers authors two options (open access or subscription) to …

TIM-4, a member of the TIM family expressed on antigen-presenting cells, binds to
phosphatidylserine exposed on the surface of apoptotic bodies. However, the significance of …

Tim-4 is a phosphatidylserine (PS) receptor that is expressed on various macrophage
subsets. It mediates phagocytosis of apoptotic cells by peritoneal macrophages. The in vivo …

The complement system is composed of more than 30 serum and membrane‐bound
proteins, all of which are needed for normal function of complement in innate and adaptive …

The underlying trigger for systemic lupus erythematosus (SLE) has remained elusive, and
multiple interacting environmental and genetic factors likely contribute to the onset and …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that may affect any
organ and presents a protean spectrum of clinical manifestations. The etiology and …

Necrosis has been thought to be an accidental or uncontrolled type of cell death rather than
programmed. Recent studies from diverse organisms show that necrosis follows a …

Reduced mechanical stress is a major cause of osteoporosis in the elderly, and the
osteocyte network, which comprises a communication system through processes and …