mRNA vaccines in disease prevention and treatment

G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …

[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery

B Sun, W Wu, EA Narasipura, Y Ma, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

Barrier membranes for guided bone regeneration (gbr): A focus on recent advances in collagen membranes

Y Ren, L Fan, S Alkildani, L Liu, S Emmert… - International journal of …, 2022 - mdpi.com
Guided bone regeneration (GBR) has become a clinically standard modality for the
treatment of localized jawbone defects. Barrier membranes play an important role in this …

Membranes for guided bone regeneration: a road from bench to bedside

P Aprile, D Letourneur… - Advanced healthcare …, 2020 - Wiley Online Library
Bone resorption can negatively influence the osseointegration of dental implants. Barrier
membranes for guided bone regeneration (GBR) are used to exclude nonosteogenic tissues …

Gene-and RNAi-activated scaffolds for bone tissue engineering: Current progress and future directions

NZ Laird, TM Acri, K Tingle, AK Salem - Advanced drug delivery reviews, 2021 - Elsevier
Large bone defects are usually managed by replacing lost bone with non-biological
prostheses or with bone grafts that come from the patient or a donor. Bone tissue …

Physical, mechanical, and biological properties of collagen membranes for guided bone regeneration: a comparative in vitro study

X Shi, X Li, Y Tian, X Qu, S Zhai, Y Liu, W Jia, Y Cui… - BMC Oral Health, 2023 - Springer
Background To provide a reference for clinical selection of collagen membranes by
analyzing the properties of three kinds of collagen membranes widely used in clinics: Bio …

Delivery of synthetic mRNAs for tissue regeneration

H Steinle, J Weber, S Stoppelkamp… - Advanced drug delivery …, 2021 - Elsevier
In recent years, nucleic acid-based therapeutics have gained increasing importance as
novel treatment options for disease prevention and treatment. Synthetic messenger RNAs …

The international society of RNA nanotechnology and nanomedicine (ISRNN): the present and future of the burgeoning field

M Chandler, B Johnson, E Khisamutdinov… - ACS …, 2021 - ACS Publications
The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) hosts an
annual meeting series focused on presenting the latest research achievements involving …

Tantalum and magnesium nanoparticles enhance the biomimetic properties and osteo-angiogenic effects of PCL membranes

J Nan, W Liu, K Zhang, Y Sun, Y Hu… - Frontiers in Bioengineering …, 2022 - frontiersin.org
Segmental bone defects, accompanied by periosteum stripping or injury, usually lead to
delayed bone union or nonunion, which have challenged orthopedic surgeons. The …

At the intersection of biomaterials and gene therapy: progress in non-viral delivery of nucleic acids

H Uludag, A Ubeda, A Ansari - Frontiers in bioengineering and …, 2019 - frontiersin.org
Biomaterials play a critical role in technologies intended to deliver therapeutic agents in
clinical settings. Recent explosion of our understanding of how cells utilize nucleic acids has …