[HTML][HTML] Dual-Action Therapeutics: DNA Alkylation and Antimicrobial Peptides for Cancer Therapy

CMC Andrés, JMP de la Lastra, EB Munguira… - …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary Conventional cancer treatments, based on chemotherapy and
radiotherapy, are often effective but suffer from serious side effects and a potential risk of …

Human and machine intelligence together drive drug repurposing in rare diseases

AP Challa, NM Zaleski, RN Jerome, RR Lavieri… - Frontiers in …, 2021 - frontiersin.org
Repurposing is an increasingly attractive method within the field of drug development for its
efficiency at identifying new therapeutic opportunities among approved drugs at greatly …

Artificial intelligence and digital biomarker in precision pathology guiding immune therapy selection and precision oncology

R Huss, J Raffler, B Märkl - Cancer Reports, 2023 - Wiley Online Library
Background The currently available immunotherapies already changed the strategy how
many cancers are treated from first to last line. Understanding even the most complex …

Machine learning and deep learning promote computational toxicology for risk assessment of chemicals

R Kusko, H Hong - Machine Learning and Deep Learning in …, 2023 - Springer
In order to advance the field of computational toxicology forward, it is vital to leverage new
machine learning and deep learning algorithms. Historically, these algorithms were limited …

QSAR facilitating safety evaluation and risk assessment

R Kusko, H Hong - QSAR in Safety Evaluation and Risk Assessment, 2023 - Elsevier
The universe of existing and potential synthetic chemicals is expanding at an exponential
pace due to advances in synthetic chemistry and manufacturing, as well as the …