Retinoblastoma is a retinal cancer that is initiated in response to biallelic loss of RB1 in
almost all cases, together with other genetic/epigenetic changes culminating in the …

The COVID‐19 pandemic is one of the most serious global challenges to delivering
affordable and equitable treatment to children with cancer we have witnessed in the last few …

Retinoblastoma is the most common primary intraocular tumor of childhood. Accurate
diagnosis at an early stage is important to maximize patient survival, globe salvage, and …

Purpose: Cancer stem cells (CSCs) are known to contribute to tumor relapses by virtue of
their chemoresistance. With the knowledge that nanoformulations can overcome drug …

Importance Adjuvant therapy is an important and effective treatment for retinoblastoma.
However, there is a lack of head-to-head clinical trials comparing 3 vs 6 cycles of CEV …

Aqueous humor contains tumor-derived cell-free DNA (cfDNA) and can serve as a liquid
biopsy for retinoblastoma. We previously associated somatic copy-number alteration …

Importance High-risk histopathologic features of retinoblastoma are useful to assess the risk
of systemic metastasis. In this era of globe salvage treatments for retinoblastoma, the …

Retinoblastoma stands as a paradigm of success in treating malignancies among pediatric
patients. Over recent decades, the approach to managing retinoblastoma has evolved …

Retinoblastoma, the primary ocular malignancy in pediatric patients, poses a substantial
threat to mortality without prompt and effective management. The prognosis for survival and …

Purpose The analysis of circulating tumor DNA (ctDNA), a fraction of total cell-free DNA
(cfDNA), might be of special interest in retinoblastoma patients. Because the accessibility to …