ACE2-independent alternative receptors for SARS-CoV-2

S Lim, M Zhang, TL Chang - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), the causative agent
of coronavirus disease 2019 (COVID-19), is highly contagious and remains a major public …

[HTML][HTML] Targeting phosphatidylserine for Cancer therapy: prospects and challenges

W Chang, H Fa, D Xiao, J Wang - Theranostics, 2020 - ncbi.nlm.nih.gov
Cancer is a leading cause of mortality and morbidity worldwide. Despite major
improvements in current therapeutic methods, ideal therapeutic strategies for improved …

A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications

GW Wright, JD Phelan, ZA Coulibaly, S Roulland… - Cancer cell, 2020 - cell.com
The development of precision medicine approaches for diffuse large B cell lymphoma
(DLBCL) is confounded by its pronounced genetic, phenotypic, and clinical heterogeneity …

The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma

CB Steen, BA Luca, MS Esfahani, A Azizi, BJ Sworder… - Cancer cell, 2021 - cell.com
Biological heterogeneity in diffuse large B cell lymphoma (DLBCL) is partly driven by cell-of-
origin subtypes and associated genomic lesions, but also by diverse cell types and cell …

[HTML][HTML] Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas

BJ Sworder, DM Kurtz, SK Alig, MJ Frank, N Shukla… - Cancer Cell, 2023 - cell.com
Most relapsed/refractory large B cell lymphoma (r/rLBCL) patients receiving anti-CD19
chimeric antigen receptor (CAR19) T cells relapse. To characterize determinants of …

Treatment resistance in diffuse large B-cell lymphoma

MY He, R Kridel - Leukemia, 2021 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous disease and represents
the most common subtype of lymphoma. Although 60–70% of all patients can be cured by …

Genetic and phenotypic attributes of splenic marginal zone lymphoma

F Bonfiglio, A Bruscaggin, F Guidetti… - Blood, The Journal …, 2022 - ashpublications.org
Splenic marginal zone B-cell lymphoma (SMZL) is a heterogeneous clinico-biological entity.
The clinical course is variable, multiple genes are mutated with no unifying mechanism, and …

The CD47-SIRPα axis is a promising target for cancer immunotherapies

Y Hao, X Zhou, Y Li, B Li, L Cheng - International Immunopharmacology, 2023 - Elsevier
Abstract Cluster of differentiation 47 (CD47) is a transmembrane protein that is ubiquitously
found on the surface of many cells in the body and uniquely overexpressed by both solid …

Toward a new molecular taxonomy of diffuse large B-cell lymphoma

D Ennishi, ED Hsi, C Steidl, DW Scott - Cancer discovery, 2020 - AACR
Diffuse large B-cell lymphoma (DLBCL) represents a grouping of clinically and biologically
heterogeneous tumors. Application of advanced molecular technology has significantly …

The role of CD47-SIRPα immune checkpoint in tumor immune evasion and innate immunotherapy

Z Li, Y Li, J Gao, Y Fu, P Hua, Y Jing, M Cai, H Wang… - Life Sciences, 2021 - Elsevier
As a transmembrane protein, CD47 plays an important role in mediating cell proliferation,
migration, phagocytosis, apoptosis, immune homeostasis, inhibition of NO signal …