Myopia

PN Baird, SM Saw, C Lanca, JA Guggenheim… - Nature reviews Disease …, 2020 - nature.com
Myopia, also known as short-sightedness or near-sightedness, is a very common condition
that typically starts in childhood. Severe forms of myopia (pathologic myopia) are associated …

[HTML][HTML] IMI–myopia genetics report

MS Tedja, AEG Haarman… - … & visual science, 2019 - iovs.arvojournals.org
IMI – Myopia Genetics Report | IOVS | ARVO Journals iovs Issues Topics For Authors About
Editorial Board Journals Home MANAGE ALERTS Access Provided By: Google Indexer Forgot …

Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

JE Craig, X Han, A Qassim, M Hassall… - Nature …, 2020 - nature.com
Glaucoma, a disease characterized by progressive optic nerve degeneration, can be
prevented through timely diagnosis and treatment. We characterize optic nerve photographs …

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

AP Khawaja, JN Cooke Bailey, NJ Wareham… - Nature …, 2018 - nature.com
Glaucoma is the leading cause of irreversible blindness globally. Despite its gravity, the
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …

[HTML][HTML] The Rotterdam Study: 2016 objectives and design update

A Hofman, GGO Brusselle, SD Murad… - European journal of …, 2015 - Springer
Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

[HTML][HTML] Degree of myopia and glaucoma risk: a dose-response meta-analysis

A Ha, CY Kim, SR Shim, IB Chang, YK Kim - American journal of …, 2022 - Elsevier
Purpose To verify the dose-response relation between the degree of myopia and open-
angle glaucoma (OAG) risk Design Dose-response meta-analysis. Methods We searched …

[HTML][HTML] An overview of myopia genetics

XB Cai, SR Shen, DF Chen, Q Zhang, ZB Jin - Experimental eye research, 2019 - Elsevier
Myopia is one of the leading ocular disorders causing visual impairment worldwide, with the
prevalence increasing rapidly. It's a significant global public health concern in 21st century …

VEGAS2: software for more flexible gene-based testing

A Mishra, S Macgregor - Twin Research and Human Genetics, 2015 - cambridge.org
Gene-based tests such as versatile gene-based association study (VEGAS) are commonly
used following per-single nucleotide polymorphism (SNP) GWAS (genome-wide association …

High prevalence of myopia in children and their parents in Hong Kong Chinese Population: the Hong Kong Children Eye Study

JC Yam, SM Tang, KW Kam, LJ Chen, M Yu… - Acta …, 2020 - Wiley Online Library
Purpose To determine the myopia prevalence in Hong Kong Chinese children and their
parents. Methods It was a population‐based cross‐sectional study. A total of 4257 children …